Approved medicine profileFDA-approved prescription drug

Tirzepatide

ZEPBOUND

LY3298176NDA 217806GIP and GLP-1 receptor agonist

ZEPBOUND is an FDA-approved tirzepatide prescription product for defined uses. The ingredient also appears in other product and online-sales contexts that belong to different regulatory records.

Active ingredientTirzepatide

The ingredient is a GIP and GLP-1 receptor agonist.

ApplicationNDA 217806

The application number distinguishes ZEPBOUND from other tirzepatide records.

Labeled usesWeight + OSA

The current label includes defined weight-management and obstructive-sleep-apnea populations.

Label boundaryBoxed warning

The current label carries a boxed warning about thyroid C-cell tumors.

Exact product record

Resolve the application before the claim.

Brand
ZEPBOUND
Active ingredient
Tirzepatide
US application
NDA 217806
Company named in current label
Lilly USA, LLC
Dosage form
Injection
Route
Subcutaneous
Approval record
ZEPBOUND NDA first approved in 2023
Label record updated
April 22, 2026
Label boundary

What this approval covers - and what it does not.

This summary stays intentionally high level. Use the current full prescribing information for complete warnings, contraindications, adverse reactions, and instructions.

FDA-labeled use

The exact approved record

The current US label covers chronic weight management in specified adults and treatment of moderate-to-severe obstructive sleep apnea in adults with obesity. The prescribing information defines the eligible populations and limitations.

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Does not transfer

An ingredient match is not product equivalence

This record describes ZEPBOUND under NDA 217806. Mounjaro is a separate tirzepatide product with a separate indication and application, while compounded or unapproved tirzepatide products do not inherit ZEPBOUND's approval or label.

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Worldwide status map

Tirzepatide across 42 countries.

This record starts with the exact US FDA medicine identity. The global and state maps keep authorization, presentation, prescription route, market status, pharmacy, and seller records separate.

Compare Tirzepatide by country →Compare Tirzepatide by US state →
Direct answers

The questions behind the medicine search.

Answers are based on the dated FDA and DailyMed records below. They are educational reporting, not a diagnosis, prescription, or treatment recommendation.

01

Are tirzepatide, Zepbound, and Mounjaro interchangeable names?

No. Tirzepatide is the active ingredient. ZEPBOUND and Mounjaro are distinct approved products with separate FDA applications and labeled uses. Ingredient-level search results should be resolved to the exact brand, application, presentation, and current label.

02

What is Zepbound FDA approved for?

The current label covers chronic weight management in specified adults and moderate-to-severe obstructive sleep apnea in adults with obesity. The label contains the full eligibility, warnings, and limitations; this page is an evidence index, not an individual treatment recommendation.

03

Does the Zepbound approval cover compounded tirzepatide?

No. FDA approval applies to the product reviewed under NDA 217806. Compounded drugs are not FDA approved before marketing, and an ingredient match does not transfer ZEPBOUND's manufacturing review, presentation, or label.

ImportantThis page is a label-navigation reference, not medical advice.

Use the current full prescribing information and a licensed clinician or pharmacist for medicine-specific decisions. Do not substitute a research product, investigational program, or unapproved seller listing for an FDA-approved product.

Open safety and verification resources →
Primary referencesCurrent ZEPBOUND prescribing informationCurrent indications, presentations, route, warnings, and label revisionNational Library of Medicine, DailyMed · Updated April 22, 2026ZEPBOUND application overview - NDA 217806Application identity, approval history, and regulatory recordU.S. Food and Drug Administration · Record checked July 17, 2026