/* Generated by scripts/build-route-css.mjs. Edit styles/site.css. */
.subpage-hero{border-bottom:1px solid var(--ink);padding:104px 0 90px}.subpage-hero h1{max-width:1020px}.subpage-hero>p{max-width:680px;color:var(--muted);margin:0;font-size:17px;line-height:1.55}.breadcrumb{color:var(--muted);font:600 var(--type-caption)/1 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.06em;flex-wrap:wrap;gap:9px;margin-bottom:70px;display:flex}.breadcrumb a:hover{color:var(--signal-text)}.local-brief-grid .eyebrow{color:#9ea198}.intent-answer-section .heading-split p a{color:var(--ink);text-decoration:underline;text-decoration-color:var(--acid);text-underline-offset:4px;font-weight:650}.quality-gates .eyebrow{color:#999c93}.product-decision-section .section-heading{align-items:end}.product-decision-section .eyebrow{color:#a4a89f}.product-decision-section .section-heading h2{max-width:720px;color:var(--white)}.product-decision-section .section-heading>p{color:#a7aba2;max-width:610px}.product-context{border-block:1px solid var(--ink);grid-template-columns:.9fr 1.1fr;gap:90px;margin-bottom:90px;padding-block:56px;display:grid}.product-context h2{letter-spacing:-.055em;margin:14px 0 0;font-size:clamp(36px,3.7vw,54px);line-height:.98}.product-context p{color:var(--muted);margin:0 0 20px;font-size:14px;line-height:1.65}.product-context a{font-size:var(--type-small);border-bottom:1px solid var(--ink);padding-bottom:3px;font-weight:700}.guide-hero{border-bottom:1px solid var(--ink);padding:44px 0 88px}.guide-hero h1{letter-spacing:-.075em;max-width:1120px;margin:24px 0 28px;font-size:clamp(56px,7vw,100px);line-height:.91}.guide-deck{max-width:740px;color:var(--muted);margin:0;font-size:18px;line-height:1.55}.guide-navigator{z-index:40;color:#f7f3ea;background:#0c0e0b;border-bottom:1px solid #343730;position:sticky;top:82px}.guide-navigator-inner{grid-template-columns:170px minmax(0,1fr);display:grid}.guide-navigator-label{border-right:1px solid #343730;flex-direction:column;justify-content:center;gap:8px;min-height:88px;padding:18px 18px 18px 0;display:flex}.guide-navigator-label span{color:#f7f3ea;font:700 var(--type-label)/1.15 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.08em}.guide-navigator-label small{color:#888c83;font:550 var(--type-micro)/1.2 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.06em}.guide-navigator-links{scrollbar-width:thin;scrollbar-color:var(--acid) #252923;grid-auto-columns:minmax(132px,1fr);grid-auto-flow:column;min-width:0;display:grid;overflow-x:auto}.guide-navigator-links a{border-right:1px solid #343730;flex-direction:column;justify-content:space-between;gap:10px;min-height:88px;padding:17px 16px;transition:background .16s,color .16s;display:flex}.guide-navigator-links a:hover{color:var(--acid);background:#1a1e19}.guide-navigator-links a:focus-visible{outline-offset:-4px}.guide-navigator-links small{color:var(--acid);font:650 var(--type-micro)/1 var(--font-geist-mono), monospace}.guide-navigator-links strong{font-size:var(--type-caption);letter-spacing:-.01em;white-space:nowrap;line-height:1.2}.editorial-byline{border-top:1px solid var(--line);color:var(--muted);font:600 var(--type-caption)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.04em;flex-wrap:wrap;align-items:center;gap:8px 18px;margin-top:28px;padding-top:17px;display:flex}.editorial-byline a{color:var(--ink);text-decoration:underline;text-decoration-color:var(--acid);text-underline-offset:3px}.editorial-byline span:nth-of-type(2){margin-left:auto}.guide-sources{padding-block:100px 120px}.guide-sources>.eyebrow{margin-bottom:28px}.guide-sources>a{border-top:1px solid var(--line);grid-template-columns:1fr 280px 34px;align-items:center;gap:25px;min-height:86px;padding:14px;transition:background .2s,padding .2s;display:grid}.guide-sources>a:last-child{border-bottom:1px solid var(--line)}.guide-sources>a:hover{background:var(--white);padding-inline:22px}.guide-sources strong{font-size:14px}.guide-sources small{color:var(--muted);font-size:var(--type-caption)}.guide-sources a>span{color:var(--acid)}.pipeline-index-hero h1{max-width:1050px}.pipeline-snapshot{grid-template-columns:repeat(4,1fr);padding-block:0 78px;display:grid}.pipeline-snapshot>div{border:1px solid var(--line);border-right:0;flex-direction:column;min-height:178px;padding:24px 22px;display:flex}.pipeline-snapshot>div:last-child{border-right:1px solid var(--line)}.pipeline-snapshot span{color:var(--muted);font:650 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-snapshot strong{letter-spacing:-.055em;margin:26px 0 18px;font-size:42px;line-height:.85}.pipeline-snapshot small{max-width:210px;color:var(--muted);font:500 var(--type-caption)/1.45 var(--font-geist-mono), monospace;margin-top:auto}.pipeline-search-opportunities{border-top:1px solid var(--ink);grid-template-columns:.7fr 1.3fr;gap:85px;padding-block:88px 100px;display:grid}.pipeline-search-opportunities h2{letter-spacing:-.063em;max-width:590px;margin:16px 0 0;font-size:clamp(40px,4.8vw,65px);line-height:.93}.pipeline-search-opportunities nav{border-top:2px solid var(--ink)}.pipeline-search-opportunities nav a{border-bottom:1px solid var(--line);grid-template-columns:1fr 26px;align-items:center;gap:24px;min-height:112px;padding:20px 6px;transition:padding .18s,background .18s;display:grid}.pipeline-search-opportunities nav a:hover{background:var(--white);padding-inline:16px}.pipeline-search-opportunities nav a>span{gap:8px;display:grid}.pipeline-search-opportunities nav strong{letter-spacing:-.03em;font-size:21px}.pipeline-search-opportunities nav small{max-width:740px;color:var(--muted);font-size:var(--type-caption);line-height:1.55}.pipeline-search-opportunities nav i{color:var(--acid);font-style:normal}.pipeline-boundary{background:var(--acid-soft);border:1px solid #8f541e;grid-template-columns:.8fr 1.6fr auto;align-items:center;gap:38px;margin-top:30px;padding:22px 24px;display:grid}.pipeline-boundary h2{letter-spacing:-.03em;margin:0;font-size:18px;line-height:1.15}.pipeline-boundary p{color:#65453c;font-size:var(--type-body-sm);margin:0;line-height:1.6}.pipeline-boundary>div{gap:8px;display:grid}.pipeline-boundary>div span{color:#65453c;font:650 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase;white-space:nowrap}.pipeline-boundary>div small{color:#65453c;max-width:180px;font-size:var(--type-body-sm);line-height:1.4}.pipeline-watchlist{border-top:1px solid var(--ink);padding-block:100px 118px}.pipeline-watchlist .section-heading h2{max-width:690px}.pipeline-watchlist-grid{border-top:2px solid var(--ink);border-left:1px solid var(--line);grid-template-columns:repeat(3,minmax(0,1fr));margin-top:48px;display:grid}.pipeline-watchlist-card{border-right:1px solid var(--line);border-bottom:1px solid var(--line);flex-direction:column;min-height:410px;padding:24px;transition:background .2s,color .2s;display:flex}.pipeline-watchlist-card:hover{background:var(--ink);color:var(--white)}.pipeline-watchlist-card>div:first-child,.pipeline-watchlist-card footer{justify-content:space-between;align-items:center;gap:20px;display:flex}.pipeline-watchlist-card>div:first-child span,.pipeline-watchlist-card>div:first-child small,.pipeline-watchlist-card footer small{color:var(--muted);font:650 var(--type-label)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-watchlist-card>div:first-child span{color:var(--acid-dark)}.pipeline-watchlist-card h3{letter-spacing:-.06em;margin:58px 0 7px;font-size:clamp(35px,3.4vw,51px);line-height:.94}.pipeline-watchlist-card>p{color:var(--muted);font:650 var(--type-caption)/1.45 var(--font-geist-mono), monospace;text-transform:uppercase;margin:0}.pipeline-watchlist-card dl{border-top:1px solid var(--line);grid-template-columns:.72fr 1.28fr;gap:18px;margin:28px 0 0;padding-top:18px;display:grid}.pipeline-watchlist-card dl div{align-content:start;gap:8px;display:grid}.pipeline-watchlist-card dt{color:var(--muted);font:650 var(--type-label)/1.2 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-watchlist-card dd{font-size:var(--type-caption);margin:0;font-weight:700;line-height:1.45}.pipeline-watchlist-card footer{margin-top:auto;padding-top:28px}.pipeline-watchlist-card footer i{color:var(--acid);font-style:normal}.pipeline-watchlist-card:hover>div:first-child small,.pipeline-watchlist-card:hover>p,.pipeline-watchlist-card:hover dt,.pipeline-watchlist-card:hover footer small{color:#aaada5}.pipeline-program-explorer{border-top:1px solid var(--ink);padding-block:100px 122px}.pipeline-program-explorer .section-heading h2{max-width:790px}.pipeline-explorer-workspace{border:1px solid var(--ink);background:var(--paper);box-shadow:12px 12px 0 var(--acid);margin:50px 12px 0 0}.pipeline-explorer-toolbar{background:var(--ink);color:var(--white);grid-template-columns:minmax(0,1.4fr) minmax(250px,.6fr);display:grid}.pipeline-explorer-toolbar>label{border-right:1px solid #4a4d46;gap:11px;padding:25px;display:grid}.pipeline-explorer-toolbar>label>span,.pipeline-explorer-toolbar>div>span{color:#aaada5;font:750 var(--type-label)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.05em}.pipeline-explorer-toolbar input{background:var(--paper);width:100%;min-height:64px;color:var(--ink);border:1px solid #666960;border-radius:0;padding:0 17px;font-size:18px;font-weight:700}.pipeline-explorer-toolbar input::placeholder{color:#74776f}.pipeline-explorer-toolbar>div{flex-direction:column;justify-content:space-between;padding:25px;display:flex}.pipeline-explorer-toolbar>div>strong{color:#aeb1a8;font:760 21px/1 var(--font-geist-mono), monospace;margin-top:25px}.pipeline-explorer-toolbar>div>strong b{color:var(--acid);letter-spacing:-.07em;font-size:46px}.pipeline-explorer-toolbar>div>small{color:#8e9189;font-size:var(--type-caption);margin-top:9px}.pipeline-explorer-filters{background:var(--paper-2)}.pipeline-filter-row{border-bottom:1px solid var(--ink);grid-template-columns:170px 1fr;min-height:78px;display:grid}.pipeline-filter-row>strong{border-right:1px solid var(--ink);font:760 var(--type-label)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase;align-items:center;padding:15px 20px;display:flex}.pipeline-filter-row>div{flex-wrap:wrap;align-items:stretch;display:flex}.pipeline-filter-row button{border:1px solid var(--ink);min-height:52px;color:var(--ink);font:inherit;cursor:pointer;background:0 0;align-items:center;gap:18px;margin:12px 0 12px 12px;padding:0 13px;display:inline-flex}.pipeline-filter-row button span{font-size:var(--type-caption);font-weight:760}.pipeline-filter-row button b{color:var(--muted);font:760 var(--type-label)/1 var(--font-geist-mono), monospace}.pipeline-filter-row button[aria-pressed=true]{background:var(--acid)}.pipeline-filter-row button[aria-pressed=true] b{color:#56631c}.pipeline-filter-row button:focus-visible{outline:3px solid var(--acid);outline-offset:2px}.pipeline-explorer-result-bar{border-bottom:1px solid var(--ink);justify-content:space-between;align-items:center;gap:20px;min-height:66px;padding:14px 20px;display:flex}.pipeline-explorer-result-bar>span{font-size:var(--type-small)}.pipeline-explorer-result-bar>span strong{color:var(--acid-dark);font:800 24px/1 var(--font-geist-mono), monospace}.pipeline-explorer-result-bar small{color:var(--muted);font-size:var(--type-caption)}.pipeline-explorer-result-bar button,.pipeline-explorer-empty button{border:1px solid var(--ink);background:var(--ink);color:var(--white);font:750 var(--type-caption)/1.2 var(--font-geist-sans), sans-serif;cursor:pointer;align-items:center;gap:14px;padding:10px 12px;display:inline-flex}.pipeline-explorer-result-bar button span{color:var(--acid);font-size:18px}.pipeline-record-list{display:grid}.pipeline-record{border-bottom:1px solid var(--line);grid-template-columns:minmax(230px,.9fr) minmax(250px,1.05fr) minmax(250px,1fr) 118px;min-height:172px;transition:background .18s,color .18s;display:grid}.pipeline-record:hover{background:var(--white)}.pipeline-record>div{border-right:1px solid var(--line);flex-direction:column;align-items:flex-start;gap:8px;min-width:0;padding:22px 20px;display:flex}.pipeline-record>div:last-child{border-right:0}.pipeline-record-identity h2{letter-spacing:-.055em;margin:11px 0 0;font-size:clamp(27px,2.6vw,38px);line-height:.95}.pipeline-record-identity>small{overflow-wrap:anywhere;color:var(--acid-dark);font:650 var(--type-label)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-record-identity>span:last-child,.pipeline-record-detail>span,.pipeline-record-check>span{color:var(--muted);font:650 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-record-identity>span:last-child{margin-top:auto}.pipeline-record-detail strong{font-size:var(--type-small);margin-top:14px;line-height:1.4}.pipeline-record-detail small{color:var(--muted);font-size:var(--type-caption);margin-top:auto;line-height:1.45}.pipeline-record-check strong{font:700 var(--type-caption)/1.4 var(--font-geist-mono), monospace;margin-top:14px}.pipeline-record-check i{color:var(--acid-dark);margin-top:auto;font-size:21px;font-style:normal}.pipeline-stage-chip-fda-review{background:var(--red);color:#69291f}.pipeline-stage-chip-china-approved{background:var(--moss);color:var(--white)}.pipeline-stage-chip-phase-3{background:var(--amber);color:#5d4d1e}.pipeline-stage-chip-earlier{background:var(--paper-2);color:var(--muted)}.pipeline-explorer-empty{flex-direction:column;justify-content:center;align-items:flex-start;min-height:430px;padding:clamp(30px,6vw,80px);display:flex}.pipeline-explorer-empty>span{color:var(--acid-dark);font:780 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-explorer-empty h3{letter-spacing:-.065em;margin:28px 0 14px;font-size:clamp(40px,5vw,67px);line-height:.92}.pipeline-explorer-empty p{color:var(--muted);font-size:var(--type-small);margin:0 0 28px}.pipeline-editorial{border-block:1px solid var(--ink);grid-template-columns:.85fr 1.15fr;gap:100px;padding-block:78px 100px;display:grid}.pipeline-editorial h2{letter-spacing:-.055em;max-width:580px;margin:15px 0 0;font-size:clamp(38px,4vw,58px);line-height:.98}.pipeline-editorial p{color:var(--muted);font-size:var(--type-body);margin:0 0 18px;line-height:1.7}.pipeline-editorial a{font-size:var(--type-small);border-bottom:1px solid var(--ink);margin-top:10px;padding-bottom:3px;font-weight:700;display:inline-block}.pipeline-profile-hero h1{max-width:1200px}.pipeline-status-line{justify-content:space-between;align-items:center;gap:25px;display:flex}.pipeline-status-badge{background:var(--amber);color:#5d4d1e;font:700 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.04em;white-space:nowrap;padding:8px 10px}.pipeline-aliases{color:var(--signal-text);font:650 var(--type-small)/1.4 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.04em;margin:-11px 0 22px}.mazdutide-hero-status-board{border:1px solid var(--ink);background:var(--paper);max-width:1200px;box-shadow:12px 12px 0 var(--acid);margin:38px 12px 38px 0}.mazdutide-hero-status-board>header{border-bottom:1px solid var(--ink);background:var(--ink);min-height:48px;color:var(--white);justify-content:space-between;align-items:center;gap:24px;padding:10px 14px;display:flex}.mazdutide-hero-status-board>header span{color:var(--acid);font:780 var(--type-label)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.05em}.mazdutide-hero-status-board>header time{color:#b8bbb2;font:720 var(--type-label)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase}.mazdutide-hero-status-board>nav{grid-template-columns:repeat(4,minmax(0,1fr));display:grid}.mazdutide-hero-status-board>nav>a{border-right:1px solid var(--ink);min-width:0;min-height:172px;color:inherit;grid-template-rows:auto 1fr auto;grid-template-columns:1fr auto;gap:11px 18px;padding:17px;transition:background .18s,color .18s;display:grid}.mazdutide-hero-status-board>nav>a:last-child{border-right:0}.mazdutide-hero-status-board small{color:var(--muted);font:760 var(--type-label)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.035em;grid-column:1}.mazdutide-hero-status-board strong{letter-spacing:-.05em;grid-column:1;align-self:center;max-width:245px;font-size:clamp(20px,2vw,28px);line-height:.98}.mazdutide-hero-status-board a>span{color:var(--muted);font-size:var(--type-caption);grid-column:1;line-height:1.4}.mazdutide-hero-status-board i{color:var(--acid-dark);grid-area:1/2/span 3;align-self:center;font-size:22px;font-style:normal}.mazdutide-hero-status-board a[data-status-kind=approved]{box-shadow:inset 0 5px 0 var(--moss)}.mazdutide-hero-status-board a[data-status-kind=not-approved]{box-shadow:inset 0 5px #bd5141}.mazdutide-hero-status-board a[data-status-kind=review]{box-shadow:inset 0 5px 0 var(--amber)}.mazdutide-hero-status-board a[data-status-kind=compare]{box-shadow:inset 0 5px 0 var(--acid)}.mazdutide-hero-status-board>nav>a:hover{background:var(--ink);color:var(--white)}.mazdutide-hero-status-board>nav>a:hover small,.mazdutide-hero-status-board>nav>a:hover span{color:#b8bbb2}.mazdutide-hero-status-board>nav>a:hover i{color:var(--acid)}.pipeline-profile-page section[id]{scroll-margin-top:188px}.pipeline-snapshot-section{padding-block:100px 112px}.pipeline-snapshot-heading{grid-template-columns:.9fr 1.1fr;align-items:end;gap:90px;padding-bottom:48px;display:grid}.pipeline-snapshot-heading h2{letter-spacing:-.068em;max-width:730px;margin:18px 0 0;font-size:clamp(44px,5.4vw,74px);line-height:.9}.pipeline-snapshot-heading>p{max-width:690px;color:var(--muted);font-size:var(--type-small);margin:0;line-height:1.72}.pipeline-facts{border-left:1px solid var(--line);grid-template-columns:repeat(4,1fr);display:grid}.pipeline-facts article{border-right:1px solid var(--line);border-bottom:1px solid var(--ink);flex-direction:column;min-height:230px;padding:24px;display:flex}.pipeline-facts article>span{color:var(--muted);font:650 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-facts strong{color:var(--signal-text);letter-spacing:-.045em;margin:66px 0 13px;font-size:27px;line-height:1}.pipeline-facts p{color:var(--muted);font-size:var(--type-small);margin:auto 0 0;line-height:1.55}.pipeline-snapshot-status{border-bottom:1px solid var(--ink);background:var(--acid);grid-template-columns:210px minmax(0,1fr) auto;align-items:center;gap:34px;min-height:118px;padding-block:22px;display:grid}.pipeline-snapshot-status>span{font:750 var(--type-label)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-snapshot-status>strong{letter-spacing:-.04em;max-width:660px;font-size:clamp(20px,2.4vw,31px);line-height:1.05}.pipeline-snapshot-status>div{justify-items:end;gap:10px;min-width:190px;display:grid}.pipeline-snapshot-status small{color:var(--ink);font:650 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-snapshot-status a{border-bottom:1px solid var(--ink);font-size:var(--type-caption);align-items:center;gap:9px;padding-bottom:3px;font-weight:800;display:inline-flex}.pipeline-priority-answer{border-block:1px solid var(--ink);grid-template-columns:.74fr 1.26fr;gap:82px;padding-block:78px;display:grid}.pipeline-priority-answer-copy h2{letter-spacing:-.067em;max-width:610px;margin:16px 0 23px;font-size:clamp(43px,5vw,70px);line-height:.91}.pipeline-priority-answer-copy p{max-width:700px;color:var(--muted);font-size:var(--type-small);margin:0;line-height:1.72}.pipeline-priority-answer-copy footer{border-top:1px solid var(--line);flex-wrap:wrap;align-items:center;gap:10px 24px;max-width:700px;margin-top:24px;padding-top:17px;display:flex}.pipeline-priority-answer-copy footer time,.pipeline-priority-answer-copy footer a{color:var(--muted);font:750 var(--type-label)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-priority-answer-copy footer a{color:var(--moss);text-decoration:underline;text-decoration-color:var(--acid-dark);text-underline-offset:4px;text-decoration-thickness:2px}.pipeline-priority-answer-copy footer a span{color:var(--acid-dark)}.pipeline-priority-answer-grid{border-top:1px solid var(--ink);border-left:1px solid var(--ink);grid-template-columns:repeat(3,minmax(0,1fr));display:grid}.pipeline-priority-answer-grid a{border-right:1px solid var(--ink);border-bottom:1px solid var(--ink);min-height:265px;color:inherit;flex-direction:column;padding:21px;transition:background .18s,color .18s;display:flex}.pipeline-priority-answer-grid a:hover{background:var(--ink);color:var(--white)}.pipeline-priority-answer-grid span{color:var(--acid-dark);font:750 var(--type-label)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-priority-answer-grid strong{letter-spacing:-.04em;margin:62px 0 13px;font-size:22px;line-height:1.04}.pipeline-priority-answer-grid small{color:var(--muted);font-size:var(--type-caption);line-height:1.5}.pipeline-priority-answer-grid i{color:var(--acid-dark);margin-top:auto;font-size:22px;font-style:normal}.pipeline-priority-answer-grid a:hover span,.pipeline-priority-answer-grid a:hover i{color:var(--acid)}.pipeline-priority-answer-grid a:hover small{color:#b9bbb5}.pipeline-source-checkpoints{padding-bottom:88px}.pipeline-source-checkpoints>header{border-bottom:1px solid var(--ink);grid-template-columns:.72fr 1.28fr;align-items:end;gap:80px;padding:22px 3px;display:grid}.pipeline-source-checkpoints>header h2{letter-spacing:-.055em;max-width:640px;margin:14px 0 0;font-size:clamp(31px,3.5vw,50px);line-height:.95}.pipeline-source-checkpoints>header>p{max-width:760px;color:var(--muted);font-size:var(--type-small);margin:0;line-height:1.65}.pipeline-source-checkpoints>div{border-left:1px solid var(--line);grid-template-columns:repeat(3,minmax(0,1fr));display:grid}.pipeline-source-checkpoints[data-pipeline-source-checkpoints=mazdutide]>div{grid-template-columns:repeat(4,minmax(0,1fr))}.pipeline-source-checkpoints>div>a{border-right:1px solid var(--line);border-bottom:1px solid var(--ink);background:color-mix(in srgb, var(--white) 36%, transparent);flex-direction:column;min-height:205px;padding:20px;display:flex}.pipeline-source-checkpoints>div>a:hover{background:var(--white)}.pipeline-source-checkpoints small{color:var(--acid-dark);font:750 var(--type-label)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-source-checkpoints strong{letter-spacing:-.045em;margin:38px 0 12px;font-size:23px;line-height:1.05}.pipeline-source-checkpoints a>b{border:1px solid var(--line);width:fit-content;color:var(--muted);font:750 var(--type-label)/1.25 var(--font-geist-mono), monospace;letter-spacing:.035em;text-transform:uppercase;margin-bottom:13px;padding:5px 7px}.pipeline-source-checkpoints a>b[data-regulatory-stage=approved]{background:color-mix(in srgb, var(--acid) 27%, transparent);color:#3f490f;border-color:#657019}.pipeline-source-checkpoints a>b[data-regulatory-stage=review]{color:#6f4d08;background:#fff1cc;border-color:#b88928}.pipeline-source-checkpoints a>b[data-regulatory-stage=not-approved]{color:#872f24;background:#ffebe6;border-color:#b75344}.pipeline-source-checkpoints a>span{color:var(--muted);font-size:var(--type-caption);line-height:1.55}.pipeline-source-checkpoints i{color:var(--acid-dark);margin-top:auto;padding-top:20px;font-size:20px;font-style:normal}.eloralintide-trial-map{border-bottom:1px solid var(--ink);padding-block:84px 104px}.eloralintide-trial-map>header{grid-template-columns:.86fr 1.14fr;align-items:end;gap:88px;display:grid}.eloralintide-trial-map>header h2{letter-spacing:-.07em;max-width:720px;margin:15px 0 0;font-size:clamp(44px,5.3vw,76px);line-height:.9}.eloralintide-trial-map>header>p{max-width:700px;color:var(--muted);font-size:var(--type-small);margin:0;line-height:1.68}.eloralintide-trial-totals{border-top:1px solid var(--ink);border-left:1px solid var(--ink);grid-template-columns:repeat(4,minmax(0,1fr));margin:48px 0 0;display:grid}.eloralintide-trial-totals>div{border-right:1px solid var(--ink);border-bottom:1px solid var(--ink);flex-direction:column;min-height:130px;padding:17px 18px;display:flex}.eloralintide-trial-totals dt{color:var(--muted);font:750 var(--type-micro)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.eloralintide-trial-totals dd{color:var(--acid-dark);letter-spacing:-.065em;margin:auto 0 0;font-size:clamp(34px,4vw,56px);font-weight:850;line-height:.85}.eloralintide-trial-grid{border-left:1px solid var(--ink);grid-template-columns:repeat(6,minmax(0,1fr));display:grid}.eloralintide-trial-grid>a{border-right:1px solid var(--ink);border-bottom:1px solid var(--ink);background:color-mix(in srgb, var(--white) 37%, transparent);min-width:0;min-height:410px;color:inherit;flex-direction:column;grid-column:span 2;padding:23px;transition:background .18s,transform .18s;display:flex}.eloralintide-trial-grid>a:nth-child(4),.eloralintide-trial-grid>a:nth-child(5){grid-column:span 3}.eloralintide-trial-grid>a:hover{z-index:1;background:var(--white);position:relative;transform:translateY(-3px)}.eloralintide-trial-grid>a>header{justify-content:space-between;align-items:flex-start;gap:20px;display:flex}.eloralintide-trial-grid>a>header span{color:var(--acid-dark);font:800 var(--type-label)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase}.eloralintide-trial-grid>a>header b{background:var(--green);color:#385537;font:750 var(--type-micro)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase;padding:5px 7px}.eloralintide-trial-grid>a>strong{letter-spacing:-.055em;max-width:360px;margin:52px 0 28px;font-size:clamp(24px,2.3vw,34px);line-height:.98}.eloralintide-trial-grid dl{border-top:1px solid var(--line);margin:0}.eloralintide-trial-grid dl>div{border-bottom:1px solid var(--line);grid-template-columns:minmax(92px,.8fr) 1.2fr;gap:15px;padding:10px 0;display:grid}.eloralintide-trial-grid dt{color:var(--muted);font:700 var(--type-micro)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.eloralintide-trial-grid dd{font-size:var(--type-label);margin:0;font-weight:750;line-height:1.45}.eloralintide-trial-grid>a>footer{justify-content:space-between;align-items:flex-end;gap:20px;margin-top:auto;padding-top:20px;display:flex}.eloralintide-trial-grid>a>footer span{color:var(--muted);font-size:var(--type-micro)}.eloralintide-trial-grid>a>footer i{color:var(--acid-dark);font-size:21px;font-style:normal}.eloralintide-result-boundary{border-left:1px solid var(--ink);grid-template-columns:repeat(2,minmax(0,1fr));display:grid}.eloralintide-result-boundary article{border-right:1px solid var(--ink);border-bottom:1px solid var(--ink);flex-direction:column;min-height:245px;padding:25px;display:flex}.eloralintide-result-boundary article:first-child{background:var(--moss);color:var(--white)}.eloralintide-result-boundary article:last-child{background:var(--amber)}.eloralintide-result-boundary span{font:750 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.eloralintide-result-boundary strong{letter-spacing:-.055em;max-width:670px;margin:45px 0 18px;font-size:clamp(26px,3vw,42px);line-height:.98}.eloralintide-result-boundary p{max-width:690px;color:inherit;font-size:var(--type-caption);opacity:.78;margin:auto 0 0;line-height:1.6}.eloralintide-trial-map-footer{border:1px solid var(--ink);border-top:0;justify-content:space-between;align-items:center;gap:30px;padding:17px 20px;display:flex}.eloralintide-trial-map-footer span{color:var(--muted);font:700 var(--type-micro)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.eloralintide-trial-map-footer a{font-size:var(--type-caption);font-weight:800}.pipeline-identity{grid-template-columns:.72fr 1.28fr;gap:100px;padding-block:100px;display:grid}.pipeline-identity h2{letter-spacing:-.055em;max-width:540px;margin:15px 0 0;font-size:clamp(38px,4vw,58px);line-height:.98}.pipeline-identity dl{border-top:1px solid var(--ink);margin:0}.pipeline-identity dl div{border-bottom:1px solid var(--line);grid-template-columns:180px 1fr;align-items:center;gap:28px;min-height:62px;display:grid}.pipeline-identity dt{color:var(--muted);font:650 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-identity dd{font-size:var(--type-body-sm);margin:0;font-weight:650}.pipeline-trial-results{border-top:1px solid var(--ink);padding-block:108px 118px}.pipeline-trial-results-heading{grid-template-columns:.9fr 1.1fr;align-items:end;gap:100px;display:grid}.pipeline-trial-results-heading h2{letter-spacing:-.065em;max-width:710px;margin:15px 0 0;font-size:clamp(42px,5.2vw,72px);line-height:.92}.pipeline-trial-results-heading>div:last-child{gap:14px;display:grid}.pipeline-trial-results-heading p{max-width:730px;color:var(--muted);font-size:var(--type-body);margin:0;line-height:1.72}.pipeline-trial-results-heading>div:last-child>span{color:var(--muted);font:650 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-trial-result-grid{border:1px solid var(--ink);margin-top:58px}.pipeline-trial-result-grid-multiple{grid-template-columns:repeat(2,minmax(0,1fr));display:grid}.pipeline-trial-result-grid-multiple .pipeline-trial-result-card+.pipeline-trial-result-card{border-left:1px solid var(--ink)}.pipeline-trial-result-card{background:var(--ink);color:var(--white);padding:30px}.pipeline-trial-result-card>header{justify-content:space-between;align-items:flex-start;gap:28px;display:flex}.pipeline-trial-result-card>header>div{flex-wrap:wrap;gap:8px;display:flex}.pipeline-trial-result-card>header span{color:#d7d8d2;font:700 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase;border:1px solid #545650;padding:7px 9px}.pipeline-trial-result-card>header small{color:var(--acid);font:700 var(--type-caption)/1.2 var(--font-geist-mono), monospace}.pipeline-trial-result-lead{border-bottom:1px solid #484a45;justify-content:space-between;align-items:flex-end;gap:36px;min-height:190px;padding-block:38px 30px;display:flex}.pipeline-trial-result-lead>div{gap:8px;display:grid}.pipeline-trial-result-lead strong{color:var(--acid);letter-spacing:-.085em;font-size:clamp(76px,10vw,144px);line-height:.75}.pipeline-trial-result-grid-multiple .pipeline-trial-result-lead strong{font-size:clamp(66px,7vw,102px)}.pipeline-trial-result-lead span,.pipeline-trial-result-lead small{color:#aaaca5;font:650 var(--type-label)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-trial-result-lead>div:last-child{text-align:right;justify-items:end}.pipeline-trial-result-lead b{letter-spacing:-.04em;font-size:23px;line-height:1}.pipeline-trial-result-answer{color:#d7d8d2;max-width:980px;font-size:var(--type-body);margin:28px 0 34px;line-height:1.72}.pipeline-trial-bars{background:#181a17;gap:19px;padding:26px;display:grid}.pipeline-trial-bars>div{gap:9px;display:grid}.pipeline-trial-bars span{color:#d7d8d2;font-size:var(--type-caption);justify-content:space-between;gap:24px;display:flex}.pipeline-trial-bars b{font-weight:700}.pipeline-trial-bars small{color:#aaaca5;font:650 var(--type-label)/1.2 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-trial-bars i{width:var(--trial-result-width);background:var(--acid);height:13px;display:block}.pipeline-trial-bars .pipeline-trial-bar-alternate i{background:#b4a4f3}.pipeline-trial-bars .pipeline-trial-bar-gain i{background:var(--red)}.pipeline-trial-chart-scale{color:#8e908a;font-size:var(--type-caption);margin:12px 0 0;line-height:1.5}.pipeline-trial-result-card dl{border-top:1px solid #484a45;grid-template-columns:repeat(2,minmax(0,1fr));margin:34px 0 0;display:grid}.pipeline-trial-result-card dl>div{border-bottom:1px solid #484a45;min-height:102px;padding:17px 18px 17px 0}.pipeline-trial-result-card dl>div:nth-child(odd){border-right:1px solid #484a45}.pipeline-trial-result-card dl>div:nth-child(2n){padding-left:18px}.pipeline-trial-result-card dt{color:#aaaca5;font:700 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase;margin-bottom:10px}.pipeline-trial-result-card dd{color:#f2f2ed;font-size:var(--type-body-sm);margin:0;line-height:1.55}.pipeline-trial-result-card dd small{color:#aaaca5;font-size:var(--type-caption);margin-top:5px;display:block}.pipeline-trial-result-card aside{background:#292618;border:1px solid #6a5c38;margin-top:28px;padding:20px}.pipeline-trial-result-card aside strong{color:var(--acid);font:700 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-trial-result-card aside p{color:#d8d1bd;font-size:var(--type-body-sm);margin:10px 0 0;line-height:1.65}.pipeline-trial-result-card>footer{justify-content:space-between;align-items:end;gap:30px;min-height:68px;padding-top:28px;display:flex}.pipeline-trial-result-card>footer a{color:var(--white);font-size:var(--type-small);border-bottom:1px solid var(--acid);font-weight:750}.pipeline-trial-result-card>footer small{color:#aaaca5;max-width:280px;font:650 var(--type-label)/1.45 var(--font-geist-mono), monospace;text-align:right;text-transform:uppercase}.pipeline-trial-result-links{border:1px solid var(--ink);border-top:0;grid-template-columns:repeat(2,minmax(0,1fr));display:grid}.pipeline-trial-result-links a{grid-template-columns:1fr auto;align-items:center;gap:28px;min-height:124px;padding:22px;display:grid}.pipeline-trial-result-links a+a{border-left:1px solid var(--ink)}.pipeline-trial-result-links a>span{gap:8px;display:grid}.pipeline-trial-result-links strong{letter-spacing:-.025em;font-size:18px}.pipeline-trial-result-links small{max-width:580px;color:var(--muted);font-size:var(--type-caption);line-height:1.5}.pipeline-trial-result-links a>b{color:var(--acid);font-size:23px}.pipeline-trial-landscape{border-top:1px solid var(--ink);padding-block:108px 118px}.pipeline-trial-landscape-heading{grid-template-columns:.9fr 1.1fr;align-items:end;gap:100px;display:grid}.pipeline-trial-landscape-heading h2{letter-spacing:-.065em;max-width:760px;margin:15px 0 0;font-size:clamp(42px,5.2vw,72px);line-height:.92}.pipeline-trial-landscape-heading>div:last-child{gap:14px;display:grid}.pipeline-trial-landscape-heading p{max-width:740px;color:var(--muted);font-size:var(--type-body);margin:0;line-height:1.72}.pipeline-trial-landscape-heading>div:last-child>span{color:var(--muted);font:650 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-trial-landscape-snapshot{border-top:1px solid var(--ink);border-left:1px solid var(--ink);grid-template-columns:repeat(5,minmax(0,1fr));margin-top:58px;display:grid}.pipeline-trial-landscape-snapshot>div{border-right:1px solid var(--ink);border-bottom:1px solid var(--ink);flex-direction:column;min-height:155px;padding:20px;display:flex}.pipeline-trial-landscape-snapshot strong{color:var(--acid-dark);font:850 clamp(38px, 4.5vw, 62px)/.9 var(--font-geist-mono), monospace;letter-spacing:-.075em}.pipeline-trial-landscape-snapshot span{max-width:170px;color:var(--muted);font-size:var(--type-caption);margin-top:auto;padding-top:20px;line-height:1.45}.pipeline-trial-landscape-grid{border-inline:1px solid var(--ink);grid-template-columns:repeat(2,minmax(0,1fr));display:grid}.pipeline-trial-landscape-grid>article{border-bottom:1px solid var(--ink);min-height:455px;padding:24px}.pipeline-trial-landscape-grid>article+article{border-left:1px solid var(--ink)}.pipeline-trial-landscape-grid article>header{border-bottom:1px solid var(--ink);justify-content:space-between;gap:30px;padding-bottom:18px;display:flex}.pipeline-trial-landscape-grid article>header span{color:var(--muted);font:750 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-trial-landscape-grid article>header strong{font-size:var(--type-caption)}.pipeline-trial-landscape-grid article>div{margin-top:22px}.pipeline-trial-landscape-status article>div,.pipeline-trial-landscape-status>div{gap:14px;display:grid}.pipeline-trial-landscape-status a{color:inherit;grid-template-columns:minmax(140px,.72fr) minmax(120px,1.28fr) 32px;align-items:center;gap:16px;display:grid}.pipeline-trial-landscape-status a>span{gap:4px;display:grid}.pipeline-trial-landscape-status a strong{font-size:var(--type-caption)}.pipeline-trial-landscape-status a small{color:var(--muted);font-size:var(--type-micro);line-height:1.35}.pipeline-trial-landscape-status a i{background:var(--paper-2);border:1px solid var(--line);height:13px;overflow:hidden}.pipeline-trial-landscape-status a i b{width:var(--pipeline-landscape-width);background:#8a8d85;height:100%;display:block}.pipeline-trial-landscape-status a i b.is-open{background:#56ad76}.pipeline-trial-landscape-status a i b.is-upcoming{background:#c5d84c}.pipeline-trial-landscape-status a i b.is-active{background:#82a9ed}.pipeline-trial-landscape-status a i b.is-closed{background:#a8aaa3}.pipeline-trial-landscape-status a em{font:800 var(--type-caption)/1 var(--font-geist-mono), monospace;text-align:right;font-style:normal}.pipeline-trial-landscape-grid article>small{color:var(--muted);font-size:var(--type-label);margin-top:24px;line-height:1.55;display:block}.pipeline-trial-landscape-phase>div{border-top:1px solid var(--line);border-left:1px solid var(--line);grid-template-columns:repeat(2,minmax(0,1fr));display:grid}.pipeline-trial-landscape-phase a{border-right:1px solid var(--line);border-bottom:1px solid var(--line);min-height:118px;color:inherit;grid-template-columns:1fr auto;align-content:space-between;gap:15px;padding:16px;display:grid}.pipeline-trial-landscape-phase a span{font-size:var(--type-caption);font-weight:800}.pipeline-trial-landscape-phase a strong{color:var(--acid-dark);font:850 30px/1 var(--font-geist-mono), monospace}.pipeline-trial-landscape-phase a i{background:var(--paper-2);grid-column:1/-1;height:7px;overflow:hidden}.pipeline-trial-landscape-phase a i b{width:var(--pipeline-landscape-width);background:var(--ink);height:100%;display:block}.pipeline-trial-landscape-geography{border:1px solid var(--ink);border-top:0}.pipeline-trial-landscape-geography>header{background:var(--ink);min-height:112px;color:var(--white);grid-template-columns:.72fr 1.28fr;align-items:center;gap:44px;padding:20px 24px;display:grid}.pipeline-trial-landscape-geography>header>div{gap:8px;display:grid}.pipeline-trial-landscape-geography>header span{color:var(--acid);font:750 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-trial-landscape-geography>header strong{font-size:var(--type-body-sm)}.pipeline-trial-landscape-geography>header p{color:#b8bbb3;font-size:var(--type-caption);margin:0;line-height:1.65}.pipeline-trial-landscape-geography>div{grid-template-columns:repeat(2,minmax(0,1fr));display:grid}.pipeline-trial-landscape-geography>div>section{min-height:390px;padding:22px}.pipeline-trial-landscape-geography>div>section+section{border-left:1px solid var(--ink)}.pipeline-trial-landscape-geography section>div{border-bottom:1px solid var(--ink);justify-content:space-between;gap:24px;padding-bottom:15px;display:flex}.pipeline-trial-landscape-geography section>div span{color:var(--muted);font-size:var(--type-label)}.pipeline-trial-landscape-geography section>a{border-bottom:1px solid var(--line);min-height:48px;color:inherit;grid-template-columns:27px 1fr auto auto;align-items:center;gap:13px;display:grid}.pipeline-trial-landscape-geography section>a>span{color:var(--acid-dark);font:750 var(--type-micro)/1 var(--font-geist-mono), monospace}.pipeline-trial-landscape-geography section>a>strong{font-size:var(--type-caption)}.pipeline-trial-landscape-geography section>a>small{color:var(--muted);font-size:var(--type-micro)}.pipeline-trial-landscape-geography section>a>b{min-width:52px;font-size:var(--type-label);text-align:right}.pipeline-trial-landscape-geography section>p{color:var(--muted);font-size:var(--type-caption);margin:28px 0 0;line-height:1.6}.pipeline-trial-landscape-actions{border-inline:1px solid var(--ink);border-bottom:1px solid var(--ink);grid-template-columns:repeat(3,minmax(0,1fr));display:grid}.pipeline-trial-landscape-actions a{min-height:126px;color:inherit;grid-template-columns:1fr auto;align-items:center;gap:24px;padding:21px;display:grid}.pipeline-trial-landscape-actions a+a{border-left:1px solid var(--ink)}.pipeline-trial-landscape-actions a>span{font-size:var(--type-caption);gap:7px;font-weight:800;display:grid}.pipeline-trial-landscape-actions small{color:var(--muted);font-size:var(--type-label);font-weight:500;line-height:1.45}.pipeline-trial-landscape-actions b{color:var(--acid-dark);font-size:22px}.pipeline-evidence{border-top:1px solid var(--ink);padding-block:100px 120px}.pipeline-evidence-columns{background:var(--ink);border:1px solid var(--ink);grid-template-columns:repeat(2,1fr);gap:1px;display:grid}.pipeline-evidence-columns>section{background:var(--paper);padding:28px}.pipeline-column-label{font:700 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase;padding:7px 9px;display:inline-flex}.evidence-label{background:var(--green);color:#284e35}.unknown-label{background:var(--red);color:#692b20}.pipeline-evidence-columns article{border-bottom:1px solid var(--line);grid-template-columns:35px 1fr;gap:12px;padding:29px 0;display:grid}.pipeline-evidence-columns article>span{color:var(--signal-text);font:650 var(--type-caption)/1 var(--font-geist-mono), monospace}.pipeline-evidence-columns h3{letter-spacing:-.035em;margin:0 0 12px;font-size:21px;line-height:1.08}.pipeline-evidence-columns p{color:var(--muted);font-size:var(--type-body-sm);grid-column:2;margin:-4px 0 0;line-height:1.7}.pipeline-answers{padding-bottom:120px}.pipeline-answer-grid{border-top:2px solid var(--ink);border-left:1px solid var(--line);grid-template-columns:repeat(3,1fr);display:grid}.pipeline-answer-grid article{border-right:1px solid var(--line);border-bottom:1px solid var(--ink);min-height:410px;padding:26px}.pipeline-answer-grid article>span{color:var(--signal-text);font:650 var(--type-caption)/1 var(--font-geist-mono), monospace}.pipeline-answer-grid h2{letter-spacing:-.045em;margin:72px 0 20px;font-size:28px;line-height:1.02}.pipeline-answer-grid p{color:var(--muted);font-size:var(--type-body-sm);margin:0;line-height:1.72}.pipeline-comparison-questions{border-top:1px solid var(--line);padding-top:105px}.pipeline-comparison-questions .pipeline-answer-grid{grid-template-columns:repeat(2,minmax(0,1fr));margin-top:46px}.pipeline-comparison-questions .pipeline-answer-grid article{min-height:360px}.pipeline-comparison-markets{border-bottom:1px solid var(--ink);padding-block:105px 115px}.pipeline-comparison-market-grid{border-top:1px solid var(--ink);border-left:1px solid var(--ink);grid-template-columns:repeat(2,minmax(0,1fr));margin-top:48px;display:grid}.pipeline-comparison-market-grid article{border-right:1px solid var(--ink);border-bottom:1px solid var(--ink);grid-template-columns:.78fr 1.22fr;gap:24px;min-height:250px;padding:22px;display:grid}.pipeline-comparison-market-grid header{flex-direction:column;display:flex}.pipeline-comparison-market-grid header>span{color:var(--acid-dark);font:800 var(--type-micro)/1 var(--font-geist-mono), monospace}.pipeline-comparison-market-grid header strong{letter-spacing:-.045em;margin-top:30px;font-size:27px;line-height:.95}.pipeline-comparison-market-grid header small{color:var(--muted);font-size:var(--type-micro);margin-top:auto;line-height:1.45}.pipeline-comparison-market-grid article>div{border-top:1px solid var(--ink)}.pipeline-comparison-market-grid a{border-bottom:1px solid var(--line);min-height:94px;font-size:var(--type-caption);grid-template-columns:1fr auto;align-items:center;gap:18px;padding:13px 3px;font-weight:800;line-height:1.35;display:grid}.pipeline-comparison-market-grid a b{color:var(--acid-dark);font-size:var(--type-body)}.pipeline-safety{background:var(--acid);color:var(--ink);grid-template-columns:.85fr 1.2fr auto;align-items:center;gap:40px;padding:28px;display:grid}.pipeline-safety>div{gap:8px;display:grid}.pipeline-safety>div span{font:700 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-safety>div strong{letter-spacing:-.035em;font-size:21px}.pipeline-safety p{font-size:var(--type-body-sm);margin:0;line-height:1.6}.pipeline-safety a{font-size:var(--type-caption);white-space:nowrap;border-bottom:1px solid var(--ink);padding-bottom:3px;font-weight:700}.pipeline-related{padding-block:100px 20px}.pipeline-related>div{border-top:2px solid var(--ink);margin-top:25px}.pipeline-related a{border-bottom:1px solid var(--line);justify-content:space-between;align-items:center;gap:30px;min-height:82px;padding:14px;transition:padding .2s,background .2s;display:flex}.pipeline-related a:hover{background:var(--white);padding-inline:22px}.pipeline-related a>span{gap:6px;font-size:15px;font-weight:700;display:grid}.pipeline-related small{color:var(--muted);font:500 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-related i{color:var(--acid);font-style:normal}.pipeline-sources>a{grid-template-columns:1fr 280px 34px}.pipeline-sources>a>span{color:var(--ink);gap:7px;display:grid}.pipeline-sources em{color:var(--muted);font-size:var(--type-caption);font-style:normal;line-height:1.4}.pipeline-sources b{color:var(--acid)}.pipeline-index-comparisons{border-top:1px solid var(--ink);padding-block:100px 120px}.pipeline-index-comparisons>div:nth-child(2){border-top:2px solid var(--ink)}.pipeline-index-comparisons>div:nth-child(2) a{border-bottom:1px solid var(--line);grid-template-columns:54px minmax(240px,1fr) minmax(230px,.65fr) 28px;align-items:center;gap:20px;min-height:88px;padding:16px 12px;transition:background .2s,padding .2s;display:grid}.pipeline-index-comparisons>div:nth-child(2) a:hover{background:var(--white);padding-inline:20px}.pipeline-index-comparisons>div:nth-child(2) span,.pipeline-index-comparisons>div:nth-child(2) small{color:var(--muted);font:600 var(--type-caption)/1.4 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-index-comparisons>div:nth-child(2) strong{letter-spacing:-.03em;font-size:20px}.pipeline-index-comparisons>div:nth-child(2) i{color:var(--acid);font-style:normal}.pipeline-index-comparisons>a{border-bottom:1px solid var(--ink);font-size:var(--type-small);gap:28px;margin-top:28px;padding-bottom:4px;font-weight:750;display:inline-flex}.pipeline-related-profiles{padding-top:30px}.pipeline-market-demand{padding-block:35px 110px}.pipeline-market-grid{border-top:2px solid var(--ink);border-left:1px solid var(--line);grid-template-columns:repeat(3,1fr);margin-top:34px;display:grid}.pipeline-market-grid a{border-right:1px solid var(--line);border-bottom:1px solid var(--line);grid-template-columns:1fr auto;align-content:space-between;gap:12px 24px;min-height:190px;padding:22px;transition:background .2s,color .2s;display:grid}.pipeline-market-grid a:hover{background:var(--ink);color:var(--white)}.pipeline-market-grid span,.pipeline-market-grid small{color:var(--muted);font:650 var(--type-label)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-market-grid span{grid-column:1/-1}.pipeline-market-grid strong{letter-spacing:-.04em;align-self:end;font-size:23px;line-height:1}.pipeline-market-grid small{grid-column:1;align-self:end}.pipeline-market-grid i{color:var(--acid);grid-area:2/2/span 2;align-self:end;font-style:normal}.pipeline-compare-index-hero h1{max-width:1050px}.pipeline-compare-boundary{border-block:1px solid var(--ink);grid-template-columns:.9fr 1.2fr auto;align-items:center;gap:50px;padding-block:26px;display:grid}.pipeline-compare-boundary>div{gap:8px;display:grid}.pipeline-compare-boundary span,.pipeline-compare-boundary small{color:var(--muted);font:650 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-compare-boundary strong{letter-spacing:-.025em;font-size:19px}.pipeline-compare-boundary p{color:var(--muted);font-size:var(--type-body-sm);margin:0;line-height:1.65}.pipeline-compare-boundary small{white-space:nowrap}.pipeline-compare-evidence-counts{grid-template-columns:repeat(4,minmax(0,1fr));padding-block:58px 0;display:grid}.pipeline-compare-evidence-counts>div{border:1px solid var(--line);border-right:0;flex-direction:column;min-height:190px;padding:22px;display:flex}.pipeline-compare-evidence-counts>div:last-child{border-right:1px solid var(--line)}.pipeline-compare-evidence-counts strong{color:var(--acid-dark);letter-spacing:-.075em;font-size:58px;line-height:.8}.pipeline-compare-evidence-counts span{font-size:var(--type-body-sm);margin-top:28px;font-weight:800}.pipeline-compare-evidence-counts small{max-width:320px;color:var(--muted);font-size:var(--type-caption);margin-top:auto;padding-top:14px;line-height:1.5}.pipeline-compare-card-grid{border-top:1px solid var(--ink);border-left:1px solid var(--line);grid-template-columns:repeat(2,1fr);padding-block:90px 120px;display:grid}.pipeline-compare-card{border-right:1px solid var(--line);border-bottom:1px solid var(--line);flex-direction:column;min-height:510px;padding:28px;transition:background .2s,color .2s;display:flex}.pipeline-compare-card:hover{background:var(--ink);color:var(--white)}.pipeline-compare-card>div:first-child{color:var(--muted);font:650 var(--type-caption)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase;justify-content:space-between;gap:30px;display:flex}.pipeline-compare-card h2{letter-spacing:-.06em;margin:78px 0 24px;font-size:clamp(38px,4.5vw,62px);line-height:.9}.pipeline-compare-card h2 b{color:var(--acid);font-weight:500}.pipeline-compare-card>p{color:var(--muted);font-size:var(--type-body-sm);-webkit-line-clamp:5;-webkit-box-orient:vertical;margin:0;line-height:1.7;display:-webkit-box;overflow:hidden}.pipeline-compare-card:hover>p,.pipeline-compare-card:hover>div:first-child{color:#a8aaa3}.pipeline-compare-card-bottom{justify-content:space-between;align-items:center;margin-top:auto;padding-top:30px;display:flex}.pipeline-compare-card-bottom span{color:var(--acid);font:700 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-compare-card-bottom i{font-style:normal}.pipeline-compare-method{border-top:1px solid var(--ink);grid-template-columns:.75fr 1.25fr;gap:100px;padding-block:100px 120px;display:grid}.pipeline-compare-method h2{letter-spacing:-.06em;max-width:500px;margin:16px 0 0;font-size:clamp(40px,4.6vw,66px);line-height:.94}.pipeline-compare-method ol{border-top:2px solid var(--ink);margin:0;padding:0;list-style:none}.pipeline-compare-method li{border-bottom:1px solid var(--line);grid-template-columns:42px 1fr;gap:18px;padding:24px 0;display:grid}.pipeline-compare-method li>span{color:var(--acid);font:650 var(--type-caption)/1 var(--font-geist-mono), monospace}.pipeline-compare-method h3{letter-spacing:-.025em;margin:0 0 8px;font-size:19px}.pipeline-compare-method p{color:var(--muted);font-size:var(--type-body-sm);margin:0;line-height:1.65}.pipeline-compare-method>a{border-bottom:1px solid var(--ink);width:fit-content;font-size:var(--type-small);grid-column:2;gap:28px;padding-bottom:4px;font-weight:750;display:inline-flex}.pipeline-comparison-hero{padding-bottom:56px}.pipeline-comparison-hero h1{max-width:1150px;font-size:clamp(54px,6.4vw,90px)}.pipeline-comparison-hero h1 b{color:var(--acid);font-weight:500}.pipeline-comparison-answer{border-block:1px solid var(--ink);grid-template-columns:.7fr 1.3fr;gap:90px;padding-block:58px;display:grid}.pipeline-comparison-answer h2{letter-spacing:-.055em;margin:14px 0 0;font-size:clamp(36px,4vw,58px);line-height:.98}.pipeline-comparison-answer>p{letter-spacing:-.025em;margin:0;font-size:clamp(20px,2.15vw,29px);line-height:1.45}.pipeline-comparison-cockpit{padding-block:94px 112px}.pipeline-comparison-cockpit-heading{grid-template-columns:.82fr 1.18fr;align-items:end;gap:88px;margin-bottom:44px;display:grid}.pipeline-comparison-cockpit-heading h2{letter-spacing:-.068em;max-width:700px;margin:15px 0 0;font-size:clamp(46px,5.5vw,76px);line-height:.9}.pipeline-comparison-cockpit-heading>p{max-width:730px;color:var(--muted);font-size:var(--type-body);margin:0;line-height:1.7}.pipeline-comparison-cockpit-board{border:1px solid var(--ink);background:var(--ink);grid-template-columns:minmax(0,1fr) minmax(280px,.72fr) minmax(0,1fr);display:grid}.pipeline-comparison-cockpit-board>article{background:var(--paper);min-width:0;min-height:540px;color:var(--ink);flex-direction:column;padding:25px;display:flex}.pipeline-comparison-cockpit-board>article header{color:var(--muted);font:750 var(--type-label)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase;justify-content:space-between;gap:20px;display:flex}.pipeline-comparison-cockpit-board>article header span{color:var(--acid-dark)}.pipeline-comparison-cockpit-board>article h3{letter-spacing:-.067em;overflow-wrap:anywhere;margin:74px 0 15px;font-size:clamp(42px,4.8vw,68px);line-height:.88}.pipeline-comparison-cockpit-board>article>p{min-height:70px;color:var(--muted);font-size:var(--type-caption);margin:0;line-height:1.58}.pipeline-comparison-cockpit-board>article dl{border-top:1px solid var(--ink);margin:32px 0}.pipeline-comparison-cockpit-board>article dl div{border-bottom:1px solid var(--line);grid-template-columns:82px 1fr;align-items:center;gap:16px;min-height:62px;display:grid}.pipeline-comparison-cockpit-board>article dt{color:var(--muted);font:750 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-cockpit-board>article dd{font-size:var(--type-caption);margin:0;font-weight:750;line-height:1.45}.pipeline-comparison-cockpit-board>article>a{border-top:1px solid var(--ink);font-size:var(--type-caption);justify-content:space-between;gap:18px;margin-top:auto;padding-top:16px;font-weight:800;display:flex}.pipeline-comparison-cockpit-board>article>a span{color:var(--acid-dark)}.pipeline-comparison-cockpit-board>aside{border-inline:1px solid var(--ink);min-width:0;color:var(--ink);background:#f1d4ce;flex-direction:column;padding:25px;display:flex}.pipeline-comparison-cockpit-board>aside>span{font:800 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-cockpit-board>aside>strong{background:var(--ink);width:fit-content;color:var(--acid);font:750 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase;margin-top:40px;padding:8px 10px}.pipeline-comparison-cockpit-board>aside h3{letter-spacing:-.058em;margin:22px 0 13px;font-size:clamp(29px,3vw,42px);line-height:.93}.pipeline-comparison-cockpit-board>aside p{color:#514b43;font-size:var(--type-caption);margin:0;line-height:1.62}.pipeline-comparison-cockpit-board>aside ul{border-top:1px solid #11130f61;margin:29px 0 0;padding:0;list-style:none}.pipeline-comparison-cockpit-board>aside li{font:750 var(--type-label)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase;border-bottom:1px solid #11130f38;padding:11px 0}.pipeline-comparison-cockpit-board>aside .button{border-color:var(--ink);background:var(--ink);width:100%;color:var(--white);justify-content:space-between;margin-top:auto}.pipeline-comparison-cockpit-board>aside .button span{color:var(--acid);font-size:19px}.pipeline-comparison-cockpit-markets{border:1px solid var(--ink);border-top:0;grid-template-columns:150px repeat(6,minmax(0,1fr));display:grid}.pipeline-comparison-cockpit-markets>span,.pipeline-comparison-cockpit-markets a{align-items:center;min-height:74px;padding:12px 14px;display:flex}.pipeline-comparison-cockpit-markets>span{background:var(--ink);color:var(--acid);font:800 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-cockpit-markets a{border-left:1px solid var(--ink);background:var(--paper);color:var(--ink);font-size:var(--type-caption);justify-content:space-between;gap:12px;font-weight:800;line-height:1.25}.pipeline-comparison-cockpit-markets a:hover{background:var(--acid)}.pipeline-comparison-cockpit-markets b{color:var(--acid-dark)}@media (width<=1100px){.pipeline-comparison-cockpit-board{grid-template-columns:1fr}.pipeline-comparison-cockpit-board>aside{border-inline:0;border-block:1px solid var(--ink);min-height:430px}}.pipeline-comparison-evidence-map{padding-block:108px 120px}.pipeline-comparison-evidence-heading{grid-template-columns:.9fr 1.1fr;align-items:end;gap:100px;display:grid}.pipeline-comparison-evidence-heading h2{letter-spacing:-.065em;max-width:720px;margin:15px 0 0;font-size:clamp(42px,5.2vw,72px);line-height:.92}.pipeline-comparison-evidence-heading>div:last-child{gap:17px;display:grid}.pipeline-comparison-evidence-heading>div:last-child strong{background:var(--ink);width:fit-content;color:var(--acid);font:750 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase;padding:8px 10px}.pipeline-comparison-evidence-heading p{max-width:760px;color:var(--muted);font-size:var(--type-body);margin:0;line-height:1.72}.pipeline-comparison-evidence-connection{border:1px solid var(--ink);grid-template-columns:minmax(0,1fr) minmax(260px,.68fr) minmax(0,1fr);margin-top:58px;display:grid}.pipeline-comparison-evidence-connection>article{background:var(--white);flex-direction:column;min-height:510px;padding:28px;display:flex}.pipeline-comparison-evidence-connection>article>span{color:var(--muted);font:750 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-evidence-connection>article h3{letter-spacing:-.065em;margin:76px 0 16px;font-size:clamp(42px,4.7vw,66px);line-height:.88}.pipeline-comparison-evidence-connection>article>p{min-height:66px;color:var(--acid-dark);font:650 var(--type-caption)/1.6 var(--font-geist-mono), monospace;margin:0}.pipeline-comparison-evidence-connection>article dl{border-top:1px solid var(--ink);margin:30px 0}.pipeline-comparison-evidence-connection>article dl div{border-bottom:1px solid var(--line);grid-template-columns:92px 1fr;align-items:center;gap:18px;min-height:66px;display:grid}.pipeline-comparison-evidence-connection>article dt{color:var(--muted);font:700 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-evidence-connection>article dd{font-size:var(--type-caption);margin:0;font-weight:700;line-height:1.45}.pipeline-comparison-evidence-connection>article>a{border-top:1px solid var(--ink);font-size:var(--type-caption);justify-content:space-between;gap:20px;margin-top:auto;padding-top:17px;font-weight:800;display:flex}.pipeline-comparison-evidence-link{border-inline:1px solid var(--ink);background:var(--acid-soft);flex-direction:column;min-width:0;padding:26px;display:flex}.pipeline-comparison-evidence-direct-randomized .pipeline-comparison-evidence-link{background:#dcebd3}.pipeline-comparison-evidence-shared-protocol .pipeline-comparison-evidence-link{background:var(--amber)}.pipeline-comparison-evidence-cross-trial .pipeline-comparison-evidence-link{background:#f1d4ce}.pipeline-comparison-evidence-link>span{font:800 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-evidence-link i{align-content:center;gap:8px;height:52px;margin:70px -26px 32px;display:grid;overflow:hidden}.pipeline-comparison-evidence-link i b{background:var(--ink);height:1px;display:block}.pipeline-comparison-evidence-cross-trial .pipeline-comparison-evidence-link i b:first-child{transform-origin:50%;transform:rotate(7deg)}.pipeline-comparison-evidence-cross-trial .pipeline-comparison-evidence-link i b:last-child{transform-origin:50%;transform:rotate(-7deg)}.pipeline-comparison-evidence-link h3{letter-spacing:-.05em;margin:0 0 16px;font-size:28px;line-height:.98}.pipeline-comparison-evidence-link p{color:#514b43;font-size:var(--type-body-sm);margin:0;line-height:1.65}.pipeline-comparison-evidence-link small{font:750 var(--type-label)/1.4 var(--font-geist-mono), monospace;text-transform:uppercase;margin-top:auto;padding-top:28px}.pipeline-comparison-registry{border:1px solid var(--ink);border-top:0}.pipeline-comparison-registry>header{background:var(--ink);min-height:110px;color:var(--white);grid-template-columns:.72fr 1.28fr;align-items:center;gap:45px;padding:20px 24px;display:grid}.pipeline-comparison-registry>header>div{gap:8px;display:grid}.pipeline-comparison-registry>header span{color:var(--acid);font:750 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-registry>header strong{font-size:var(--type-body-sm)}.pipeline-comparison-registry>header p{color:#b8bbb3;max-width:760px;font-size:var(--type-caption);margin:0;line-height:1.65}.pipeline-comparison-registry>div{grid-template-columns:repeat(2,1fr);display:grid}.pipeline-comparison-registry article{background:var(--white);flex-direction:column;min-height:380px;padding:26px;display:flex}.pipeline-comparison-registry article+article{border-left:1px solid var(--ink)}.pipeline-comparison-registry article>span{color:var(--muted);font:750 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-registry article>strong{color:var(--acid-dark);font:850 clamp(46px, 5vw, 70px)/.85 var(--font-geist-mono), monospace;letter-spacing:-.07em;margin:45px 0 8px}.pipeline-comparison-registry article>strong.pipeline-registry-outside{letter-spacing:-.055em;font-size:clamp(32px,3.5vw,48px)}.pipeline-comparison-registry article h3{letter-spacing:-.04em;margin:0 0 24px;font-size:24px;line-height:1.05}.pipeline-comparison-registry article>p{max-width:620px;color:var(--muted);font-size:var(--type-caption);margin:8px 0 24px;line-height:1.65}.pipeline-comparison-registry article dl{border-top:1px solid var(--line);border-left:1px solid var(--line);grid-template-columns:repeat(3,1fr);margin:0 0 28px;display:grid}.pipeline-comparison-registry article dl div{border-right:1px solid var(--line);border-bottom:1px solid var(--line);min-height:82px;padding:12px}.pipeline-comparison-registry article dt{color:var(--muted);font:700 var(--type-micro)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-registry article dd{font-size:var(--type-body-sm);margin:12px 0 0;font-weight:800}.pipeline-comparison-registry article>a{border-top:1px solid var(--ink);font-size:var(--type-caption);justify-content:space-between;gap:20px;margin-top:auto;padding-top:16px;font-weight:800;display:flex}.pipeline-comparison-registry article>a b{color:var(--acid)}.pipeline-comparison-registry>footer{border-top:1px solid var(--ink);background:var(--paper-2);grid-template-columns:1fr auto;align-items:center;gap:30px;padding:17px 24px;display:grid}.pipeline-comparison-registry>footer span{color:var(--muted);font-size:var(--type-label);line-height:1.55}.pipeline-comparison-registry>footer a{font-size:var(--type-caption);white-space:nowrap;font-weight:800}.pipeline-comparison-decision-matrix{border:1px solid var(--ink);border-top:0}.pipeline-comparison-decision-matrix>div,.pipeline-comparison-decision-matrix article{grid-template-columns:.72fr .62fr 1.26fr;align-items:center;gap:24px;display:grid}.pipeline-comparison-decision-matrix>div{background:var(--ink);min-height:46px;color:var(--white);font:750 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase;padding:10px 18px}.pipeline-comparison-decision-matrix article{border-bottom:1px solid var(--line);min-height:92px;padding:15px 18px}.pipeline-comparison-decision-matrix article:last-child{border-bottom:0}.pipeline-comparison-decision-matrix article strong{font-size:var(--type-body-sm)}.pipeline-comparison-decision-matrix article b{background:var(--acid-soft);width:fit-content;color:var(--acid-dark);font:750 var(--type-label)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase;padding:7px 9px}.pipeline-comparison-decision-matrix article p{color:var(--muted);font-size:var(--type-caption);margin:0;line-height:1.55}.pipeline-comparison-identities{background:var(--ink);border-inline:1px solid var(--ink);grid-template-columns:repeat(2,1fr);gap:1px;padding-block:90px 120px;display:grid}.pipeline-comparison-identities article{background:var(--paper);flex-direction:column;padding:30px;display:flex}.pipeline-comparison-identities article>div:first-child{color:var(--muted);font:650 var(--type-caption)/1.3 var(--font-geist-mono), monospace;text-transform:uppercase;justify-content:space-between;gap:20px;display:flex}.pipeline-comparison-identities h2{letter-spacing:-.065em;margin:72px 0 14px;font-size:clamp(45px,5vw,72px);line-height:.9}.pipeline-comparison-identities article>p{min-height:50px;color:var(--acid);font:650 var(--type-small)/1.5 var(--font-geist-mono), monospace;margin:0 0 30px}.pipeline-comparison-identities dl{border-top:1px solid var(--ink);margin:0 0 35px}.pipeline-comparison-identities dl div{border-bottom:1px solid var(--line);grid-template-columns:120px 1fr;align-items:center;gap:18px;min-height:64px;display:grid}.pipeline-comparison-identities dt{color:var(--muted);font:650 var(--type-label)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase}.pipeline-comparison-identities dd{font-size:var(--type-small);margin:0;font-weight:650;line-height:1.45}.pipeline-comparison-identities article>a{border-top:1px solid var(--ink);font-size:var(--type-small);justify-content:space-between;gap:25px;margin-top:auto;padding:15px 0;font-weight:750;display:flex}.pipeline-comparison-matrix{padding-block:110px}.pipeline-comparison-table-wrap{border-top:2px solid var(--ink);overflow-x:auto}.pipeline-comparison-table-wrap table{min-width:940px}.pipeline-comparison-table-wrap caption{clip:rect(0 0 0 0);white-space:nowrap;width:1px;height:1px;position:absolute;overflow:hidden}.pipeline-comparison-table-wrap th,.pipeline-comparison-table-wrap td{vertical-align:top}.pipeline-comparison-table-wrap thead th{background:var(--ink);color:var(--white)}.pipeline-comparison-table-wrap tbody th{width:150px;font-size:var(--type-small)}.pipeline-comparison-table-wrap tbody td{width:25%;color:var(--muted);font-size:var(--type-small);line-height:1.55}.pipeline-comparison-table-wrap tbody td:last-child{color:var(--ink);background:var(--acid-soft)}.pipeline-comparison-boundary{background:var(--ink);color:var(--white);padding-block:90px}.pipeline-comparison-boundary>div{grid-template-columns:.8fr 1.2fr;gap:100px;display:grid}.pipeline-comparison-boundary h2{letter-spacing:-.06em;max-width:620px;margin:15px 0 0;font-size:clamp(40px,4.7vw,68px);line-height:.94}.pipeline-comparison-boundary p{color:#c4c5bf;letter-spacing:-.02em;margin:0;font-size:clamp(19px,2vw,27px);line-height:1.55}.pipeline-comparison-rules{grid-template-columns:.72fr 1.28fr;gap:100px;padding-block:100px 120px;display:grid}.pipeline-comparison-rules h2{letter-spacing:-.055em;margin:15px 0 0;font-size:clamp(40px,4vw,58px);line-height:.96}.pipeline-comparison-rules ol{border-top:2px solid var(--ink);margin:0;padding:0;list-style:none}.pipeline-comparison-rules li{border-bottom:1px solid var(--line);grid-template-columns:48px 1fr;gap:20px;padding:26px 0;display:grid}.pipeline-comparison-rules li span{color:var(--acid);font:650 var(--type-caption)/1 var(--font-geist-mono), monospace}.pipeline-comparison-rules li p{font-size:var(--type-body);margin:0;line-height:1.65}.vendor-evidence-map .eyebrow{color:var(--vendor-health)}.vendor-footprint-table .availability{width:auto;font:650 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.04em;padding:5px 7px;display:inline-flex}.calculator-method .eyebrow{color:var(--ink)}.clinical-trial-monitor-answer.is-review_required:before{background:var(--coral)}.data-download-section .eyebrow{color:#aeb1a8}.data-table .availability{width:auto;font:650 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.04em;padding:5px 7px;display:inline-flex}.data-dictionary-section .eyebrow{color:var(--ink)}.access-data-table .status-chip{white-space:normal;max-width:220px;line-height:1.25;display:inline-flex}.analytics-section-heading.compact{grid-template-columns:1fr}.compare-board-finder .eyebrow{color:var(--acid-dark)}.compare-evidence-heading .eyebrow{color:#b5c3b7}.compare-source-status.is-confirmed{background:#edf3ed;border-color:#9eb8a3}.compare-source-status.is-confirmed strong{color:#295a36}.compare-source-status.is-parser_review,.compare-source-status.is-access_blocked{background:#fff1ec;border-color:#d7a08f}.compare-source-status.is-parser_review strong,.compare-source-status.is-access_blocked strong{color:#963720}.compare-boundary .eyebrow{color:#b5c3b7}.pair-compare-hero .breadcrumb{margin-bottom:44px}.vendor-pair-index .section-heading{margin-bottom:38px}.source-registry-hero .breadcrumb{margin-bottom:62px}.source-boundary .eyebrow{color:#b6c0b7}.nav-wrap>*{min-width:0}.desktop-nav a[aria-current=page]{color:var(--ink);text-decoration:underline;text-decoration-color:var(--acid);text-underline-offset:7px;text-decoration-thickness:2px}.more-nav{position:relative}.more-nav summary{color:#383a35;font-size:var(--type-body);cursor:pointer;align-items:center;gap:7px;font-weight:600;list-style:none;display:flex}.more-nav summary::-webkit-details-marker{display:none}.more-nav summary span{color:var(--acid);font:700 14px/1 var(--font-geist-mono), monospace}.more-nav[open] summary span{transform:rotate(45deg)}.more-nav-panel{width:min(760px,100vw - 40px);max-height:calc(100vh - 96px);color:var(--white);box-shadow:10px 10px 0 var(--acid);background:#353731;grid-template-columns:repeat(3,1fr);gap:1px;padding:12px;display:grid;position:absolute;top:35px;right:-20px;overflow-y:auto}.more-nav-panel section{background:var(--ink);min-width:0;padding:8px}.more-nav-panel section>span,.mobile-more-links section>span{color:var(--acid);font:650 var(--type-label)/1 var(--font-geist-mono), monospace;text-transform:uppercase;letter-spacing:.08em;padding:8px 10px;display:block}.more-nav-panel a{min-height:78px;color:var(--white);border-top:1px solid #353731;gap:5px;padding:12px 10px;display:grid}.more-nav-panel a:hover{color:var(--white);background:#1c1e1a}.more-nav-panel strong{font-size:var(--type-body-sm)}.more-nav-panel small{color:#94978e;font-size:var(--type-label);line-height:1.4}.menu-toggle{border:1px solid var(--ink);min-height:42px;color:var(--ink);cursor:pointer;background:0 0;align-items:center;gap:18px;padding:0 13px;display:none}.menu-toggle span{font-size:var(--type-small);text-transform:uppercase;font-weight:700}.menu-toggle i{color:var(--acid);font:700 17px/1 var(--font-geist-mono), monospace;font-style:normal}.mobile-site-menu{background:var(--ink);max-height:0;color:var(--white);transition:max-height .28s;overflow:hidden}.mobile-site-menu[data-open=true]{border-top:1px solid #363833;max-height:calc(100vh - 68px);overflow-y:auto}.mobile-site-menu>div{grid-template-columns:1.2fr .8fr;gap:30px;padding-block:18px 26px;display:grid}.mobile-primary-links,.mobile-more-links{align-content:start;display:grid}.mobile-primary-links a{border-bottom:1px solid #363833;grid-template-columns:35px 1fr auto;align-items:center;gap:12px;min-height:58px;display:grid}.mobile-primary-links a>span{color:#7e8178;font:650 var(--type-label)/1 var(--font-geist-mono), monospace}.mobile-primary-links a strong{font-size:17px}.mobile-primary-links a i{color:var(--acid);font-style:normal}.mobile-more-links{gap:18px}.mobile-more-links section{align-content:start;display:grid}.mobile-more-links a{border-bottom:1px solid #363833;gap:4px;padding:12px 2px;display:grid}.mobile-more-links strong{color:#dedfd9;font-size:var(--type-small)}.mobile-more-links small{color:#85887f;font-size:var(--type-label);line-height:1.35}.product-visual-section .eyebrow,.product-visual-section .section-heading>p{color:#9da098}.atlas-hero .editorial-byline,.safety-center-hero .editorial-byline{margin-top:0}.safety-current-grid .eyebrow{color:#9b9e95}.review-rules-grid .eyebrow{color:#969990}.catalog-review-heading nav a.active{background:var(--ink);color:var(--white)}.contextual-comparison-launchpad{padding-block:clamp(74px,8vw,116px)}.contextual-comparison-shell{border:1px solid var(--ink);background:var(--ink);color:var(--white);box-shadow:14px 14px 0 var(--acid);grid-template-columns:minmax(0,.88fr) minmax(560px,1.12fr);display:grid}.contextual-comparison-copy{flex-direction:column;min-width:0;padding:clamp(28px,4.5vw,68px);display:flex}.contextual-comparison-copy .eyebrow{color:var(--acid-on-dark)}.contextual-comparison-copy h2{letter-spacing:-.072em;max-width:690px;margin:19px 0 29px;font-size:clamp(45px,5vw,72px);line-height:.88}.contextual-comparison-copy>p{color:#b9bbb5;max-width:660px;font-size:var(--type-body-sm);margin:0;line-height:1.72}.contextual-comparison-copy>div{flex-wrap:wrap;gap:10px;margin-top:auto;padding-top:52px;display:flex}.contextual-comparison-copy .button{min-height:52px;font-size:var(--type-caption)}.contextual-comparison-copy .button-acid{border-color:var(--acid);background:var(--acid);color:var(--ink)}.contextual-comparison-copy .button-acid span{font-size:19px}.contextual-comparison-copy .button-dark-outline{color:var(--white);background:0 0;border-color:#585b54}.contextual-comparison-copy .button-dark-outline:hover{border-color:var(--white);background:var(--white);color:var(--ink)}.contextual-comparison-board{background:var(--ink);grid-template-rows:minmax(250px,1fr) minmax(190px,.72fr) auto;grid-template-columns:1fr 1fr;gap:1px;min-width:0;display:grid}.contextual-comparison-board>article{background:var(--paper);min-width:0;color:var(--ink);flex-direction:column;padding:22px;display:flex}.contextual-comparison-board>article header{justify-content:space-between;align-items:start;gap:20px;display:flex}.contextual-comparison-board>article header span{color:var(--acid-dark);font:850 34px/.8 var(--font-geist-mono), monospace;letter-spacing:-.07em}.contextual-comparison-board>article header small,.contextual-comparison-country>span{color:var(--muted);font:760 var(--type-micro)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase}.contextual-comparison-board>article>strong{letter-spacing:-.055em;overflow-wrap:anywhere;margin:54px 0 12px;font-size:clamp(25px,2.5vw,37px);line-height:.92}.contextual-comparison-board>article>p{color:var(--muted);font-size:var(--type-caption);margin:0;line-height:1.5}.contextual-comparison-board>article>footer{color:var(--acid-dark);font:760 var(--type-micro)/1.4 var(--font-geist-mono), monospace;text-transform:uppercase;margin-top:auto;padding-top:24px}.contextual-comparison-country{background:var(--moss);color:var(--white);grid-column:1/-1;grid-template-rows:auto auto auto;grid-template-columns:1fr auto;align-content:center;gap:8px 28px;padding:24px;display:grid}.contextual-comparison-country>span{color:var(--acid-on-dark)}.contextual-comparison-country>strong{letter-spacing:-.07em;font-size:clamp(34px,4vw,55px);line-height:.86}.contextual-comparison-country>small{color:#b9c8bc;font:700 var(--type-micro)/1.35 var(--font-geist-mono), monospace;text-transform:uppercase;grid-column:1}.contextual-comparison-country>p{color:#cbd5cd;max-width:210px;font-size:var(--type-caption);text-align:right;grid-area:1/2/span 3;align-self:center;margin:0;line-height:1.55}.contextual-comparison-lenses{background:var(--acid);color:var(--ink);grid-column:1/-1;grid-template-columns:repeat(4,minmax(0,1fr));display:grid}.contextual-comparison-lenses span{font:850 var(--type-micro)/1.25 var(--font-geist-mono), monospace;text-transform:uppercase;border-right:1px solid #11130f8c;padding:12px 14px}.contextual-comparison-lenses span:last-child{border-right:0}.comparison-intent-handoff>header .eyebrow{color:var(--acid-on-dark)}.peptide-comparison-boundary .eyebrow,.peptide-pair-reading-rules .eyebrow{color:#969990}.product-vendor-pairs .section-heading{margin-bottom:42px}.market-matrix-hero .breadcrumb{margin-bottom:76px}.market-matrix-rules .eyebrow{color:#9da098}.site-search-hero .breadcrumb{margin-bottom:44px}.site-search-page-results .site-search-hero .breadcrumb{margin-bottom:23px}.site-search-results.is-single{grid-template-columns:1fr}.site-search-results.is-single .site-search-record{grid-template-rows:auto 1fr auto;grid-template-columns:minmax(225px,.8fr) minmax(300px,1.2fr);column-gap:42px;min-height:300px;display:grid}.site-search-results.is-single .site-search-record>header{grid-column:1/-1}.site-search-results.is-single .site-search-record-title{grid-area:2/1;align-self:center;margin-top:22px}.site-search-results.is-single .site-search-record-description{font-size:var(--type-body);grid-area:2/2;align-self:center;margin:22px 0}.site-search-results.is-single .site-search-record>footer{grid-column:1/-1}.site-search-rules .eyebrow{color:#9da098}.contact-hero .breadcrumb{margin-bottom:78px}.regions-hero .breadcrumb{margin-bottom:72px}.region-hero .breadcrumb{margin-bottom:70px}.region-snapshot-card .eyebrow{color:#989b92}.region-record-head .status-chip{white-space:normal;grid-column:2;justify-self:start;margin-top:7px;line-height:1.3}.hero>*,.heading-split>*,.vendor-hero-grid>*,.product-context>*,.seller-claim-strip>div>*,.review-evidence-heading>*,.peptide-compare-hero-grid>*,.peptide-pair-hero-grid>*,.region-hero-grid>*,.site-search-hero-grid>*,.atlas-hero-grid>*,.evidence-compare-heading>*,.research-price-compare-intro>*,.evidence-comparison-answers>*{min-width:0}.vendor-hero h1,.section-heading h2{overflow-wrap:anywhere}@media (width<=1180px){.section-shell,.footer-grid,.footer-bottom{width:min(100% - 40px,1320px)}.contextual-comparison-shell{grid-template-columns:1fr}.contextual-comparison-copy>p{max-width:820px}.desktop-nav{display:none}.nav-wrap{grid-template-columns:1fr auto auto;gap:12px}.menu-toggle{display:inline-flex}.hero{grid-template-columns:1fr;gap:55px}}@media (width<=1050px){.nav-wrap{grid-template-columns:1fr auto auto}.hero{grid-template-columns:1fr;gap:60px}}@media (width<=900px){.pipeline-market-grid{grid-template-columns:repeat(2,1fr)}.pipeline-comparison-market-grid article{grid-template-columns:1fr}.pipeline-index-comparisons>div:nth-child(2) a{grid-template-columns:42px 1fr 24px}.pipeline-index-comparisons>div:nth-child(2) small{grid-column:2}.pipeline-index-comparisons>div:nth-child(2) i{grid-area:1/3/span 2}.pipeline-compare-boundary{grid-template-columns:1fr;gap:20px}.pipeline-compare-boundary small{white-space:normal}.pipeline-compare-method,.pipeline-comparison-answer,.pipeline-comparison-boundary>div,.pipeline-comparison-rules,.pipeline-comparison-evidence-heading,.pipeline-comparison-cockpit-heading{grid-template-columns:1fr;gap:45px}.pipeline-compare-method>a{grid-column:1}.pipeline-comparison-evidence-connection,.pipeline-comparison-cockpit-board{grid-template-columns:1fr}.pipeline-comparison-cockpit-board>aside{border-inline:0;border-block:1px solid var(--ink);min-height:430px}.pipeline-comparison-cockpit-markets{grid-template-columns:repeat(3,minmax(0,1fr))}.pipeline-comparison-cockpit-markets>span{grid-column:1/-1}.pipeline-comparison-cockpit-markets a:nth-child(2),.pipeline-comparison-cockpit-markets a:nth-child(5){border-left:0}.pipeline-comparison-cockpit-markets a:nth-child(n+5){border-top:1px solid var(--ink)}.pipeline-comparison-evidence-link{border-inline:0;border-block:1px solid var(--ink);min-height:330px}.pipeline-comparison-evidence-link i{margin-block:40px 25px}.pipeline-comparison-registry>header{grid-template-columns:1fr;gap:18px}.pipeline-trial-landscape-heading{grid-template-columns:1fr;gap:35px}.pipeline-trial-landscape-snapshot{grid-template-columns:repeat(3,minmax(0,1fr))}.pipeline-trial-landscape-grid{grid-template-columns:1fr}.pipeline-trial-landscape-grid>article+article{border-left:0}.pipeline-trial-landscape-geography>header{grid-template-columns:1fr;gap:18px}.pipeline-trial-landscape-actions{grid-template-columns:1fr}.pipeline-trial-landscape-actions a+a{border-left:0;border-top:1px solid var(--ink)}.pipeline-comparison-identities{grid-template-columns:1fr}.pipeline-comparison-identities article+article{border-top:1px solid var(--ink)}.pipeline-snapshot{grid-template-columns:repeat(2,1fr)}.pipeline-snapshot>div:nth-child(2){border-right:1px solid var(--line)}.pipeline-watchlist-grid{grid-template-columns:repeat(2,minmax(0,1fr))}.pipeline-record{grid-template-columns:minmax(210px,.8fr) minmax(240px,1fr) minmax(220px,1fr)}.pipeline-record-check{grid-column:1/-1;grid-template-columns:1fr auto auto;min-height:66px;align-items:center!important;display:grid!important}.pipeline-record-check strong,.pipeline-record-check i{margin-top:0}.heading-split,.decision-hub-heading,.evidence-desk-heading{grid-template-columns:1fr;gap:20px}}@media (width<=760px){.contextual-comparison-launchpad{padding-block:64px 76px}.contextual-comparison-shell{box-shadow:9px 9px 0 var(--acid)}.contextual-comparison-copy{padding:28px 20px 34px}.contextual-comparison-copy h2{font-size:clamp(39px,12.5vw,55px)}.contextual-comparison-copy>div{grid-template-columns:1fr;padding-top:35px;display:grid}.contextual-comparison-copy .button{justify-content:space-between;width:100%}.contextual-comparison-board{grid-template-rows:auto;grid-template-columns:1fr}.contextual-comparison-board>article{min-height:260px}.contextual-comparison-board>article>strong{font-size:31px}.contextual-comparison-country,.contextual-comparison-lenses{grid-column:1}.contextual-comparison-country{grid-template-rows:auto;grid-template-columns:1fr;min-height:200px}.contextual-comparison-country>span,.contextual-comparison-country>strong,.contextual-comparison-country>small,.contextual-comparison-country>p{grid-area:auto/1}.contextual-comparison-country>p{text-align:left;max-width:320px}.contextual-comparison-lenses{grid-template-columns:repeat(2,minmax(0,1fr))}.contextual-comparison-lenses span:nth-child(2){border-right:0}.contextual-comparison-lenses span:nth-child(n+3){border-top:1px solid #11130f8c}.pipeline-compare-card-grid,.pipeline-compare-evidence-counts{grid-template-columns:1fr}.pipeline-compare-evidence-counts>div{border-right:1px solid var(--line);border-bottom:0;min-height:150px}.pipeline-compare-evidence-counts>div:last-child{border-bottom:1px solid var(--line)}.pipeline-compare-card{min-height:440px}.pipeline-compare-card h2{margin-top:54px}.pipeline-comparison-identities{padding-block:70px 90px}.pipeline-comparison-identities article{padding:22px}.pipeline-comparison-identities h2{margin-top:50px}.pipeline-comparison-answer,.pipeline-comparison-boundary,.pipeline-comparison-rules,.pipeline-comparison-matrix,.pipeline-comparison-evidence-map{padding-block:78px}.pipeline-comparison-cockpit{padding-block:70px 82px}.pipeline-comparison-cockpit-board>article{min-height:500px;padding:22px}.pipeline-comparison-cockpit-board>article h3{margin-top:55px}.pipeline-comparison-cockpit-markets{grid-template-columns:1fr}.pipeline-comparison-cockpit-markets>span,.pipeline-comparison-cockpit-markets a{min-height:58px}.pipeline-comparison-cockpit-markets a{border-left:0;border-top:1px solid var(--ink)}.pipeline-comparison-decision-matrix>div{display:none}.pipeline-comparison-decision-matrix article{grid-template-columns:1fr;gap:10px;padding-block:20px}.pipeline-comparison-registry>div{grid-template-columns:1fr}.pipeline-comparison-registry article+article{border-left:0;border-top:1px solid var(--ink)}.pipeline-comparison-registry article dl{grid-template-columns:1fr}.pipeline-comparison-registry>footer{grid-template-columns:1fr;gap:14px}.pipeline-comparison-registry>footer a{white-space:normal}.pipeline-snapshot{grid-template-columns:1fr}.pipeline-snapshot>div{border-right:1px solid var(--line);border-bottom:0;min-height:150px}.pipeline-snapshot>div:last-child{border-bottom:1px solid var(--line)}.pipeline-watchlist{padding-block:76px 88px}.pipeline-watchlist-grid{grid-template-columns:1fr;margin-top:34px}.pipeline-watchlist-card{min-height:360px}.section-shell,.footer-grid,.footer-bottom{width:min(100% - 32px,1320px)}.regions-hero .breadcrumb,.region-hero .breadcrumb{margin-bottom:46px}.nav-wrap{width:calc(100% - 24px);min-height:68px}.brand-copy small,.nav-actions,.nav-cta{display:none}.nav-wrap{grid-template-columns:1fr auto}.menu-toggle{min-height:38px}.mobile-site-menu>div{grid-template-columns:1fr;gap:22px}.brand-mark{width:36px;height:36px}.hero{min-height:auto;padding:62px 0 74px}.hero h1,.subpage-hero h1,.location-hero h1,.product-hero h1{letter-spacing:-.07em;font-size:clamp(48px,15vw,72px)}.site-search-hero .breadcrumb{margin-bottom:43px}.site-search-page-results .site-search-hero .breadcrumb{margin-bottom:20px}.market-matrix-hero .breadcrumb{margin-bottom:43px}.atlas-hero .breadcrumb,.medicine-index-hero .breadcrumb,.medicine-profile-hero .breadcrumb,.safety-center-hero .breadcrumb{margin-bottom:40px}.button{justify-content:space-between;width:100%}.heading-split{grid-template-columns:1fr;gap:20px}.section-heading h2,.method-copy h2,.safety-callout h2,.local-brief-grid h2,.quality-gates h2,.correction-section h2{font-size:40px}.footer-grid{grid-template-columns:1fr 1fr;gap:45px 25px}.footer-grid>div:first-child{grid-column:span 2}.subpage-hero{padding:70px 0 60px}.index-list>a>.status-chip{display:none}.breadcrumb{margin-bottom:45px}.product-context,.guide-lead,.guide-limit{grid-template-columns:1fr;gap:38px}.vendor-index-promo,.report-promo,.pipeline-promo,.calculator-promo,.data-index-promo{grid-template-columns:1fr;gap:22px;padding:25px}.vendor-index-promo>a,.report-promo>a,.pipeline-promo>a,.calculator-promo>a,.data-index-promo>a{justify-content:space-between}.pipeline-boundary,.pipeline-editorial,.pipeline-identity,.pipeline-trial-results-heading,.pipeline-snapshot-heading,.pipeline-priority-answer{grid-template-columns:1fr;gap:35px}.pipeline-program-explorer{padding-block:76px 94px}.pipeline-explorer-workspace{box-shadow:8px 8px 0 var(--acid);margin-right:8px}.pipeline-explorer-toolbar{grid-template-columns:1fr}.pipeline-explorer-toolbar>label{border-bottom:1px solid #4a4d46;border-right:0}.pipeline-explorer-toolbar>div{min-height:170px}.pipeline-filter-row{grid-template-columns:1fr}.pipeline-filter-row>strong{border-right:0;border-bottom:1px solid var(--line);min-height:52px}.pipeline-filter-row>div{padding:6px 8px 14px}.pipeline-filter-row button{flex:145px;justify-content:space-between;margin:8px 4px 0}.pipeline-explorer-result-bar{flex-direction:column;align-items:flex-start}.pipeline-explorer-result-bar button{justify-content:space-between;width:100%}.pipeline-status-line{flex-direction:column;align-items:flex-start;gap:14px}.pipeline-status-badge{white-space:normal;max-width:100%;line-height:1.35}.mazdutide-hero-status-board{box-shadow:8px 8px 0 var(--acid);margin:32px 8px 34px 0}.mazdutide-hero-status-board>header{flex-direction:column;align-items:flex-start;gap:5px}.mazdutide-hero-status-board>nav{grid-template-columns:repeat(2,minmax(0,1fr))}.mazdutide-hero-status-board>nav>a{border-bottom:1px solid var(--ink);min-height:158px;padding:14px}.mazdutide-hero-status-board>nav>a:nth-child(2n){border-right:0}.mazdutide-hero-status-board>nav>a:nth-last-child(-n+2){border-bottom:0}.mazdutide-hero-status-board strong{font-size:clamp(18px,5.4vw,22px)}.mazdutide-hero-status-board i{font-size:19px}.pipeline-record{grid-template-columns:1fr}.pipeline-record>div{border-right:0;border-bottom:1px solid var(--line);min-height:128px}.pipeline-record>div:last-child{border-bottom:0}.pipeline-record-check{grid-column:auto;min-height:66px!important}.pipeline-facts{grid-template-columns:repeat(2,1fr)}.pipeline-snapshot-section{padding-block:76px 88px}.pipeline-snapshot-status{grid-template-columns:1fr;gap:12px;padding:22px 20px}.pipeline-snapshot-status>div{justify-items:start;min-width:0;margin-top:6px}.pipeline-profile-page section[id]{scroll-margin-top:164px}.pipeline-priority-answer-grid{grid-template-columns:1fr}.pipeline-priority-answer-grid a{grid-template-rows:auto auto 1fr;grid-template-columns:minmax(0,1fr) auto;gap:8px 18px;min-height:126px;display:grid}.pipeline-priority-answer-grid span,.pipeline-priority-answer-grid strong,.pipeline-priority-answer-grid small{grid-column:1}.pipeline-priority-answer-grid strong{margin:8px 0 0}.pipeline-priority-answer-grid i{grid-area:1/2/span 3;align-self:center;margin-top:0}.eloralintide-trial-map{padding-block:70px 82px}.eloralintide-trial-map>header{grid-template-columns:1fr;gap:28px}.eloralintide-trial-map>header h2{font-size:clamp(42px,12vw,58px)}.eloralintide-trial-totals{grid-template-columns:repeat(2,minmax(0,1fr));margin-top:36px}.eloralintide-trial-totals>div{min-height:112px;padding:14px}.eloralintide-trial-totals dd{font-size:34px}.eloralintide-trial-grid{grid-template-columns:1fr}.eloralintide-trial-grid>a,.eloralintide-trial-grid>a:nth-child(4),.eloralintide-trial-grid>a:nth-child(5){grid-column:auto;min-height:365px;padding:20px}.eloralintide-trial-grid>a>strong{margin-top:42px;font-size:29px}.eloralintide-result-boundary{grid-template-columns:1fr}.eloralintide-result-boundary article{min-height:230px;padding:21px}.eloralintide-result-boundary strong{margin-top:38px;font-size:30px}.eloralintide-trial-map-footer{flex-direction:column;align-items:flex-start}.pipeline-evidence-columns,.pipeline-answer-grid{grid-template-columns:1fr}.pipeline-safety{grid-template-columns:1fr;gap:20px}.pipeline-safety a{white-space:normal;width:fit-content}.pipeline-sources>a{grid-template-columns:1fr 24px}.pipeline-sources small{grid-column:1}.pipeline-sources b{grid-area:1/2/span 2}.pipeline-market-grid,.pipeline-trial-result-grid-multiple,.pipeline-trial-result-links{grid-template-columns:1fr}.pipeline-trial-result-grid-multiple .pipeline-trial-result-card+.pipeline-trial-result-card,.pipeline-trial-result-links a+a{border-left:0;border-top:1px solid var(--ink)}.pipeline-trial-landscape{padding-block:78px 90px}.pipeline-trial-landscape-snapshot{grid-template-columns:1fr}.pipeline-trial-landscape-snapshot>div{min-height:125px}.pipeline-trial-landscape-grid>article{min-height:0;padding:20px}.pipeline-trial-landscape-status a{grid-template-columns:minmax(115px,.85fr) minmax(85px,1.15fr) 26px;gap:10px}.pipeline-trial-landscape-phase>div,.pipeline-trial-landscape-geography>div{grid-template-columns:1fr}.pipeline-trial-landscape-geography>div>section{min-height:0;padding:19px}.pipeline-trial-landscape-geography>div>section+section{border-left:0;border-top:1px solid var(--ink)}.pipeline-trial-landscape-geography section>a{grid-template-columns:24px 1fr auto;gap:10px;min-height:58px}.pipeline-trial-landscape-geography section>a>small{grid-column:2}.pipeline-trial-landscape-geography section>a>b{grid-area:1/3/span 2}.pipeline-comparison-market-grid{grid-template-columns:1fr}.guide-hero{padding-bottom:65px}.guide-hero h1{font-size:clamp(48px,14vw,72px)}.pipeline-profile-eloralintide .pipeline-profile-hero h1{font-size:clamp(44px,11.5vw,56px)}.guide-navigator-inner{grid-template-columns:1fr;width:100%}.guide-navigator-label{display:none}.guide-navigator-links{grid-auto-columns:minmax(128px,42vw);padding-left:20px}.guide-navigator-links a{min-height:72px;padding:13px 14px}.editorial-byline{grid-template-columns:1fr;display:grid}.editorial-byline span:nth-of-type(2){margin-left:0}.guide-deck{font-size:15px}.guide-sources>a{grid-template-columns:1fr 24px}.guide-sources small{grid-column:1}.guide-sources a>span{grid-area:1/2/span 2}.guide-sources.pipeline-sources>a>span{grid-area:1/1;min-width:0}.pipeline-sources strong,.pipeline-sources em{overflow-wrap:anywhere}.pair-compare-hero .breadcrumb{margin-bottom:34px}.source-registry-hero .breadcrumb{margin-bottom:42px}.contact-hero .breadcrumb{margin-bottom:56px}}.global-status-hero .breadcrumb{margin-bottom:72px}.global-popular-checks .section-heading p,.global-popular-checks .eyebrow{color:#aeb1a8}.compound-country-quick-section .section-heading{margin-bottom:46px}.global-trial-atlas .eyebrow{color:var(--acid)}@media (width<=700px){.global-status-hero .breadcrumb{margin-bottom:46px}.compound-country-quick-section .section-heading{margin-bottom:34px}.global-dataset-lookup-section .section-heading{gap:18px}}.compound-country-hero .editorial-byline{margin-top:28px}.compound-country-region .section-heading{margin-bottom:44px}.region-intent-grid article.is-active{background:var(--ink);color:var(--white)}.region-intent-grid article.is-active p{color:#b8bbb3}.region-intent-grid article.is-active footer{border-color:#555851}.region-intent-grid article.is-active footer a{color:var(--white)}.compound-dataset-table-section .section-heading>p a{border-bottom:1px solid var(--ink);color:var(--ink);margin-top:10px;font-weight:750;display:inline-flex}.document-access-hero>.section-shell{padding-block:44px 96px}.document-access-hero .breadcrumb{color:#9da098}.document-access-hero .breadcrumb a{color:var(--white)}.document-access-hero .eyebrow{color:var(--acid)}@media (width<=700px){.document-access-hero>.section-shell{padding-block:35px 76px}}.data-catalog-freshness.is-review_due:before{background:#ad6a00}.data-catalog-freshness.is-stale:before{background:var(--coral)}.data-catalog-freshness-label.is-review_due:before{background:#ad6a00}.data-catalog-freshness-label.is-stale:before{background:var(--coral)}.country-clinical-trial-section .eyebrow{color:var(--acid-on-dark)}.country-compound-snapshot .status-chip{text-align:right;max-width:15rem}.country-compound-navigator .guide-navigator-links{overscroll-behavior-x:contain}.country-compound-navigator .guide-navigator-links strong{white-space:normal;overflow-wrap:anywhere}@media (width<=760px){.country-compound-detail-hero .breadcrumb{margin-bottom:34px}.country-compound-snapshot .status-chip{white-space:normal;overflow-wrap:anywhere;min-width:0;max-width:11rem;line-height:1.3}.country-compound-navigator .guide-navigator-links a{min-height:80px}}.global-verification-report .editorial-byline{margin-top:30px}.coa-checker-hero .breadcrumb{margin-bottom:74px}.coa-checker-interpretation .section-heading p{color:#aeb1a8}@media (width<=700px){.coa-checker-hero .breadcrumb{margin-bottom:55px}}@media print{.coa-checker-page .site-header,.coa-checker-page+.site-footer,.coa-audit-toolbar button,.coa-audit-summary>button{display:none!important}}.publisher-embed-section .section-heading p{color:#b6b9b1}.publisher-boundaries .section-shell>div{border-top:1px solid;grid-template-columns:repeat(3,1fr);display:grid}@media (width<=700px){.publisher-boundaries .section-shell>div{grid-template-columns:1fr}}.regulators-hero .breadcrumb{margin-bottom:46px}@media (width<=760px){.regulators-hero .breadcrumb{margin-bottom:34px}}.fda-report-hero .breadcrumb{margin-bottom:52px}.fda-hero-answer>ol li.is-current:after{border-color:var(--acid);background:var(--acid)}.fda-report-hero .editorial-byline{margin-top:38px}@media (width<=900px){.pipeline-source-checkpoints>header{grid-template-columns:1fr;gap:30px}.pipeline-source-checkpoints>div,.pipeline-source-checkpoints[data-pipeline-source-checkpoints=mazdutide]>div,.global-current-status-grid{grid-template-columns:1fr}.pipeline-source-checkpoints>div>a{min-height:175px}.pipeline-profile-mazdutide .pipeline-profile-hero h1{font-size:clamp(44px,12vw,64px)}}.fda-status-board .section-shell{grid-template-columns:1.2fr .8fr;gap:80px;padding-block:70px;display:grid}.fda-decision-ladder li.is-current:after{border-color:var(--acid);background:var(--acid);box-shadow:0 0 0 5px color-mix(in srgb, var(--acid) 20%, transparent)}.fda-substance-proposal.is-recommended strong{color:#244126;background:#dce9cf}.fda-update-policy .section-shell{grid-template-columns:170px 1fr 1fr;align-items:start;gap:65px;display:grid}@media (width<=1100px){.fda-status-board .section-shell{grid-template-columns:1fr;gap:50px}.fda-update-policy .section-shell{grid-template-columns:140px 1fr}}@media (width<=720px){.pipeline-comparison-questions .pipeline-answer-grid{grid-template-columns:1fr}.fda-report-hero .breadcrumb{margin-bottom:35px}.fda-status-board .section-shell{padding-block:62px}.fda-update-policy .section-shell{grid-template-columns:1fr;gap:28px}}.weight-loss-trial-stats .section-shell{border-left:1px solid var(--ink);grid-template-columns:repeat(4,minmax(0,1fr));padding-block:0;display:grid}.weight-loss-trial-stats .section-shell>div{border-right:1px solid var(--ink);flex-direction:column;justify-content:space-between;min-height:174px;padding:20px;display:flex}.trial-chart{border:1px solid var(--ink);background:var(--paper-2);border-bottom-width:2px;height:520px;margin:0 0 48px 54px;position:relative}.trial-chart-point.is-selected{z-index:4;width:32px;height:32px;box-shadow:0 0 0 5px #11120f2e}.trial-chart-point:hover>span,.trial-chart-point:focus-visible>span,.trial-chart-point.is-selected>span{gap:3px;display:grid}.trial-chart-legend span i.phase-3{background:#ff563d}.trial-data-downloads .section-shell{grid-template-columns:.76fr 1.24fr;gap:92px;padding-block:104px 118px;display:grid}@media (width<=900px){.weight-loss-trial-stats .section-shell{grid-template-columns:repeat(2,minmax(0,1fr))}.weight-loss-trial-stats .section-shell>div:nth-child(n+3){border-top:1px solid var(--ink)}.weight-loss-trial-answer,.trial-explorer-heading,.trial-context-heading,.trial-pair-builder-heading,.trial-estimand-guide,.trial-data-downloads .section-shell,.trial-related-paths,.trial-dataset-method,.trial-data-dictionary,.trial-dataset-citation{grid-template-columns:1fr;gap:50px}}@media (width<=720px){.weight-loss-trial-stats .section-shell>div{min-height:138px;padding:15px}.trial-chart{height:420px;margin-left:40px}.trial-chart-point.is-selected>span{display:none}.trial-data-downloads .section-shell{padding-block:78px 90px}}.site-header-dark{color:#f7f3ea;backdrop-filter:none;background:#080d0b;border-bottom-color:#2b302c}.site-header-dark .nav-wrap{min-height:84px}.site-header-dark .brand-copy strong{color:#f7f3ea;letter-spacing:.035em;text-transform:uppercase;font-size:18px;font-weight:760}.site-header-dark .brand-copy small{display:none}.site-header-dark .desktop-nav a{color:#d7d9d3}.site-header-dark .desktop-nav a:hover{color:var(--acid)}.site-header-dark .desktop-nav a[aria-current=page]{color:#fff}.site-header-dark .nav-search{color:#f7f3ea;background:#0d1210;border-color:#4c514c;min-height:48px;padding-inline:16px}.site-header-dark .nav-search:hover{border-color:var(--acid);background:#151a17}.site-header-dark .nav-search kbd{color:#a9ada7;background:#161b18;border-color:#484d48}.site-header-dark .menu-toggle{color:#f7f3ea}.site-header-dark .mobile-site-menu{color:#f7f3ea;background:#0b100e}.site-header-dark .mobile-primary-links a,.site-header-dark .mobile-more-links section,.site-header-dark .mobile-more-links a{border-color:#303530}.site-header-dark .mobile-more-links small,.site-header-dark .mobile-more-links section>span{color:#9da19b}.market-signal{background:#0a0f0d;padding:25px 0 30px}@media (width<=900px){.site-header-dark .nav-wrap{min-height:70px}.search-momentum-heading,.pipeline-search-opportunities{grid-template-columns:1fr;gap:28px}}@media (width<=700px){.site-header-dark .brand-copy strong{font-size:15px}.market-signal{padding-top:20px}.pipeline-search-opportunities{padding-block:70px 82px}}.partners-hero .breadcrumb{margin-bottom:78px}.partners-value .eyebrow{color:#aeb1a8}.partner-pilot-hero .breadcrumb{margin-bottom:78px}.partner-pilot-timeline .eyebrow,.partner-pilot-timeline .section-heading>p{color:#aeb1a8}@media (width<=700px){.partners-hero .breadcrumb,.partner-pilot-hero .breadcrumb{margin-bottom:56px}}.transparency-hero .breadcrumb,.transparency-record-hero .breadcrumb,.provider-report-hero .breadcrumb{margin-bottom:74px}.transparency-criteria-section .eyebrow,.transparency-criteria-section .section-heading>p,.transparency-scorecard-section .eyebrow,.transparency-scorecard-section .section-heading>p{color:#afb2a9}.transparency-provider-card.is-standard{background:var(--acid-soft)}.transparency-provider-card.is-standard:hover,.transparency-provider-card.is-standard:focus-visible{background:var(--acid);color:var(--ink)}.transparency-provider-card.is-standard .transparency-mini-bar i{background:var(--moss)}.transparency-provider-card.is-standard:hover>p,.transparency-provider-card.is-standard:focus-visible>p{color:#3d3f39}.transparency-record-score.is-standard{background:var(--acid-soft)}.provider-evidence-comparison-heading .eyebrow{color:var(--acid)}.provider-report-boundary .section-shell{grid-template-columns:180px 1fr;gap:45px;display:grid}.provider-report-ranking .eyebrow,.provider-report-ranking .section-heading>p{color:#adb0a7}.provider-ranking-list em.is-met{color:var(--acid)}.transparency-standard-pill.is-met{background:var(--green);color:var(--moss)}@media (width<=720px){.transparency-hero .breadcrumb,.transparency-record-hero .breadcrumb,.provider-report-hero .breadcrumb{margin-bottom:55px}.transparency-boundary,.provider-report-boundary .section-shell{grid-template-columns:1fr;gap:14px}}.trend-caveat .section-shell{grid-template-columns:260px 1fr;align-items:start;gap:65px;display:grid}.trend-snapshot .eyebrow,.trend-snapshot .section-heading>p{color:#a9aca4}@media (width<=720px){.trend-caveat .section-shell{grid-template-columns:1fr;gap:12px}}.ghk-identity-strip .section-shell{grid-template-columns:repeat(4,minmax(0,1fr));display:grid}.ghk-name-map .section-shell{grid-template-columns:.66fr 1.34fr;gap:90px;display:grid}.ghk-name-map .eyebrow{color:#a5a99f}.ghk-name-ledger .is-warning>span{color:var(--red)}.ghk-cu-guide .guide-sources em{color:var(--muted);font-size:var(--type-micro);margin-top:7px;font-style:normal;line-height:1.45;display:block}.ghk-cu-guide .guide-sources b{color:var(--acid);font-size:var(--type-body)}@media (width<=1100px){.ghk-name-map .section-shell,.ghk-search-context{grid-template-columns:1fr;gap:48px}}@media (width<=720px){.ghk-identity-strip .section-shell,.ghk-category-grid,.ghk-answer-grid,.ghk-path-grid{grid-template-columns:1fr}}@media (width<=700px){.site-search-results.is-single .site-search-record{min-height:360px;display:flex}.site-search-results.is-single .site-search-record-title{margin-top:28px}.site-search-results.is-single .site-search-record-description{font-size:var(--type-body-sm);margin:27px 0}}